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Clinical features of brain metastasis from salivary gland tumors.

Publication ,  Journal Article
Venteicher, AS; Walcott, BP; Sheth, SA; Snuderl, M; Patel, AP; Curry, WT; Nahed, BV
Published in: J Clin Neurosci
November 2013

Salivary gland tumors comprise a group of 24 tumor subtypes with a wide range of clinical behaviors and propensities for metastasis. Several prognostic factors have been identified that help predict the development of systemic metastases, most commonly to the lung, liver, or bone. Metastases to the brain are rare. To better understand the behavior of salivary gland tumors that metastasise to the brain, we performed a retrospective cohort analysis on a series of patients to highlight features of their medical and surgical management. From 2007 to 2011, a database of 4117 elective craniotomies were queried at a single institution to identify patients surgically treated for salivary gland metastases to the brain. Three patients were identified. Histologic subtypes included salivary duct carcinoma, poorly differentiated carcinoma, and papillary mucinous adenocarcinoma. They had all undergone previous treatment for their primary malignancy. The mean time to intracranial metastasis was 48 months from initial diagnosis (range, 14-91 months). Treatment for intracranial metastases included surgical resection, whole brain radiation, stereotactic radiosurgery, and chemotherapy. Intracranial metastases from salivary gland tumors are rare, present years after diagnosis of the primary tumor, and are treatable with multimodality therapy.

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Published In

J Clin Neurosci

DOI

EISSN

1532-2653

Publication Date

November 2013

Volume

20

Issue

11

Start / End Page

1533 / 1537

Location

Scotland

Related Subject Headings

  • Salivary Gland Neoplasms
  • Retrospective Studies
  • Neurology & Neurosurgery
  • Middle Aged
  • Male
  • Humans
  • Female
  • Combined Modality Therapy
  • Cohort Studies
  • Brain Neoplasms
 

Citation

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Chicago
ICMJE
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Venteicher, A. S., Walcott, B. P., Sheth, S. A., Snuderl, M., Patel, A. P., Curry, W. T., & Nahed, B. V. (2013). Clinical features of brain metastasis from salivary gland tumors. J Clin Neurosci, 20(11), 1533–1537. https://doi.org/10.1016/j.jocn.2012.11.024
Venteicher, Andrew S., Brian P. Walcott, Sameer A. Sheth, Matija Snuderl, Anoop P. Patel, William T. Curry, and Brian V. Nahed. “Clinical features of brain metastasis from salivary gland tumors.J Clin Neurosci 20, no. 11 (November 2013): 1533–37. https://doi.org/10.1016/j.jocn.2012.11.024.
Venteicher AS, Walcott BP, Sheth SA, Snuderl M, Patel AP, Curry WT, et al. Clinical features of brain metastasis from salivary gland tumors. J Clin Neurosci. 2013 Nov;20(11):1533–7.
Venteicher, Andrew S., et al. “Clinical features of brain metastasis from salivary gland tumors.J Clin Neurosci, vol. 20, no. 11, Nov. 2013, pp. 1533–37. Pubmed, doi:10.1016/j.jocn.2012.11.024.
Venteicher AS, Walcott BP, Sheth SA, Snuderl M, Patel AP, Curry WT, Nahed BV. Clinical features of brain metastasis from salivary gland tumors. J Clin Neurosci. 2013 Nov;20(11):1533–1537.
Journal cover image

Published In

J Clin Neurosci

DOI

EISSN

1532-2653

Publication Date

November 2013

Volume

20

Issue

11

Start / End Page

1533 / 1537

Location

Scotland

Related Subject Headings

  • Salivary Gland Neoplasms
  • Retrospective Studies
  • Neurology & Neurosurgery
  • Middle Aged
  • Male
  • Humans
  • Female
  • Combined Modality Therapy
  • Cohort Studies
  • Brain Neoplasms