Patient-Reported Outcomes of Breast Reconstruction: Does the Quality of Decisions Matter?

Journal Article (Journal Article)


Little is known about how the quality of decisions influences patient-reported outcomes (PROs). We hypothesized that higher decision quality for breast reconstruction would be independently associated with better PROs.


We conducted a prospective cohort study of patients undergoing mastectomy with or without reconstruction. Patients were enrolled before surgery and followed for 18 months. We used BREAST-Q scales to measure PROs and linear regression models to explore the relationship between decision quality (based on knowledge and preference concordance) and PROs. Final models were adjusted for baseline BREAST-Q score, radiation, chemotherapy, and major complications.


The cohort included 101 patients who completed baseline and 18-month surveys. Breast reconstruction was independently associated with higher satisfaction with breasts (β = 20.2, p = 0.0002), psychosocial well-being (β = 14.4, p = 0.006), and sexual well-being (β = 15.7, p = 0.007), but not physical well-being. Patients who made a high-quality decision had similar PROs as patients who did not. Among patients undergoing mastectomy with reconstruction, higher decision quality was associated with lower psychosocial well-being (β = -14.2, p = 0.01).


Breast reconstruction was associated with better PROs in some but not all domains. Overall, making a high-quality decision was not associated with better PROs. However, patients who did not have reconstruction had a trend toward better well-being after making a high-quality decision, whereas patients who did have reconstruction had poorer well-being after making a high-quality decision. Additional research on the relationship between decision quality and PROs is needed.

Full Text

Duke Authors

Cited Authors

  • Chettri, SR; Pignone, MP; Deal, AM; Sepucha, KR; Blizard, LB; Huh, R; Liu, Y-J; Ubel, PA; Lee, CN

Published Date

  • March 2023

Published In

Volume / Issue

  • 30 / 3

Start / End Page

  • 1891 - 1900

PubMed ID

  • 36437408

Electronic International Standard Serial Number (EISSN)

  • 1534-4681

International Standard Serial Number (ISSN)

  • 1068-9265

Digital Object Identifier (DOI)

  • 10.1245/s10434-022-12785-6


  • eng