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Neuromonitoring in neonatal critical care part I: neonatal encephalopathy and neonates with possible seizures.

Publication ,  Journal Article
El-Dib, M; Abend, NS; Austin, T; Boylan, G; Chock, V; Cilio, MR; Greisen, G; Hellström-Westas, L; Lemmers, P; Pellicer, A; Pressler, RM ...
Published in: Pediatr Res
July 2023

The blooming of neonatal neurocritical care over the last decade reflects substantial advances in neuromonitoring and neuroprotection. The most commonly used brain monitoring tools in the neonatal intensive care unit (NICU) are amplitude integrated EEG (aEEG), full multichannel continuous EEG (cEEG), and near-infrared spectroscopy (NIRS). While some published guidelines address individual tools, there is no consensus on consistent, efficient, and beneficial use of these modalities in common NICU scenarios. This work reviews current evidence to assist decision making for best utilization of neuromonitoring modalities in neonates with encephalopathy or with possible seizures. Neuromonitoring approaches in extremely premature and critically ill neonates are discussed separately in the companion paper. IMPACT: Neuromonitoring techniques hold promise for improving neonatal care. For neonatal encephalopathy, aEEG can assist in screening for eligibility for therapeutic hypothermia, though should not be used to exclude otherwise eligible neonates. Continuous cEEG, aEEG and NIRS through rewarming can assist in prognostication. For neonates with possible seizures, cEEG is the gold standard for detection and diagnosis. If not available, aEEG as a screening tool is superior to clinical assessment alone. The use of seizure detection algorithms can help with timely seizures detection at the bedside.

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Published In

Pediatr Res

DOI

EISSN

1530-0447

Publication Date

July 2023

Volume

94

Issue

1

Start / End Page

64 / 73

Location

United States

Related Subject Headings

  • Seizures
  • Pediatrics
  • Intensive Care Units, Neonatal
  • Infant, Newborn, Diseases
  • Infant, Newborn
  • Humans
  • Electroencephalography
  • Critical Care
  • Brain Diseases
  • 3213 Paediatrics
 

Citation

APA
Chicago
ICMJE
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El-Dib, M., Abend, N. S., Austin, T., Boylan, G., Chock, V., Cilio, M. R., … Newborn Brain Society Guidelines and Publications Committee, . (2023). Neuromonitoring in neonatal critical care part I: neonatal encephalopathy and neonates with possible seizures. Pediatr Res, 94(1), 64–73. https://doi.org/10.1038/s41390-022-02393-1
El-Dib, Mohamed, Nicholas S. Abend, Topun Austin, Geraldine Boylan, Valerie Chock, M Roberta Cilio, Gorm Greisen, et al. “Neuromonitoring in neonatal critical care part I: neonatal encephalopathy and neonates with possible seizures.Pediatr Res 94, no. 1 (July 2023): 64–73. https://doi.org/10.1038/s41390-022-02393-1.
El-Dib M, Abend NS, Austin T, Boylan G, Chock V, Cilio MR, et al. Neuromonitoring in neonatal critical care part I: neonatal encephalopathy and neonates with possible seizures. Pediatr Res. 2023 Jul;94(1):64–73.
El-Dib, Mohamed, et al. “Neuromonitoring in neonatal critical care part I: neonatal encephalopathy and neonates with possible seizures.Pediatr Res, vol. 94, no. 1, July 2023, pp. 64–73. Pubmed, doi:10.1038/s41390-022-02393-1.
El-Dib M, Abend NS, Austin T, Boylan G, Chock V, Cilio MR, Greisen G, Hellström-Westas L, Lemmers P, Pellicer A, Pressler RM, Sansevere A, Tsuchida T, Vanhatalo S, Wusthoff CJ, Newborn Brain Society Guidelines and Publications Committee. Neuromonitoring in neonatal critical care part I: neonatal encephalopathy and neonates with possible seizures. Pediatr Res. 2023 Jul;94(1):64–73.

Published In

Pediatr Res

DOI

EISSN

1530-0447

Publication Date

July 2023

Volume

94

Issue

1

Start / End Page

64 / 73

Location

United States

Related Subject Headings

  • Seizures
  • Pediatrics
  • Intensive Care Units, Neonatal
  • Infant, Newborn, Diseases
  • Infant, Newborn
  • Humans
  • Electroencephalography
  • Critical Care
  • Brain Diseases
  • 3213 Paediatrics