Repeatability of Rotational 3-D Shear Wave Elasticity Imaging Measurements in Skeletal Muscle.

Journal Article (Journal Article)

Shear wave elasticity imaging (SWEI) usually assumes an isotropic material; however, skeletal muscle is typically modeled as a transversely isotropic material with independent shear wave speeds in the directions along and across the muscle fibers. To capture these direction-dependent properties, we implemented a rotational 3-D SWEI system that measures the shear wave speed both along and across the fibers in a single 3-D acquisition, with automatic detection of the muscle fiber orientation. We tested and examined the repeatability of this system's measurements in the vastus lateralis of 10 healthy volunteers. The average coefficient of variation of the measurements from this 3-D SWEI system was 5.3% along the fibers and 8.1% across the fibers. When compared with estimated respective 2-D SWEI values of 16.0% and 83.4%, these results suggest using 3-D SWEI has the potential to improve the precision of SWEI measurements in muscle. Additionally, we observed no significant difference in shear wave speed between the dominant and non-dominant legs along (p = 0.26) or across (p = 0.65) the muscle fibers.

Full Text

Duke Authors

Cited Authors

  • Paley, CT; Knight, AE; Jin, FQ; Moavenzadeh, SR; Pietrosimone, LS; Hobson-Webb, LD; Rouze, NC; Palmeri, ML; Nightingale, KR

Published Date

  • March 2023

Published In

Volume / Issue

  • 49 / 3

Start / End Page

  • 750 - 760

PubMed ID

  • 36543617

Pubmed Central ID

  • PMC10065087

Electronic International Standard Serial Number (EISSN)

  • 1879-291X

Digital Object Identifier (DOI)

  • 10.1016/j.ultrasmedbio.2022.10.012


  • eng

Conference Location

  • England