Hemophagocytic Lymphohistiocytosis in Langerhans Cell Histiocytosis: A Case Report and Review of the Literature.

Journal Article (Journal Article;Review)

A toddler undergoing treatment for refractory Langerhans cell histiocytosis (LCH) developed concurrent hemophagocytic lymphohistiocytosis (HLH). These are thought to be distinct histiocytic disorders, with different pathophysiologies, diagnostic criteria, and treatments. HLH in a patient with LCH is thought to be quite rare. In this report, we review the presentation of our patient, as well as review the existing literature of other pediatric patients who have been diagnosed with both LCH and HLH.

Full Text

Duke Authors

Cited Authors

  • Hinson, ARP; Patel, N; Kaplan, J

Published Date

  • January 2021

Published In

Volume / Issue

  • 43 / 1

Start / End Page

  • 24 - 27

PubMed ID

  • 31725543

Pubmed Central ID

  • PMC7737855

Electronic International Standard Serial Number (EISSN)

  • 1536-3678

Digital Object Identifier (DOI)

  • 10.1097/MPH.0000000000001652


  • eng

Conference Location

  • United States