Solution NMR studies of the plant peptide hormone CEP inform function.
Publication
, Journal Article
Bobay, BG; DiGennaro, P; Scholl, E; Imin, N; Djordjevic, MA; Mck Bird, D
Published in: FEBS Lett
December 11, 2013
The C-terminally Encoded Peptide (CEP) family of regulatory peptides controls root development in vascular plants. Here, we present the first NMR structures of CEP. We show that root-knot nematode (RKN: Meloidogyne spp.) also encodes CEP, presumably to mimic plant CEP as part of their stereotypic, parasitic interaction with vascular plants. Molecular dynamics simulations of plant- and nematode-encoded CEP displaying known posttranslational modifications (PTM) provided insight into the structural effects of PTM and the conformational plasticity and rigidity of CEP. Potential mechanisms of action are discussed with respect to the structure and sampling of conformational space.
Duke Scholars
Published In
FEBS Lett
DOI
EISSN
1873-3468
Publication Date
December 11, 2013
Volume
587
Issue
24
Start / End Page
3979 / 3985
Location
England
Related Subject Headings
- Tylenchoidea
- Sequence Homology, Amino Acid
- Root Nodules, Plant
- Plants
- Plant Growth Regulators
- Plant Diseases
- Nuclear Magnetic Resonance, Biomolecular
- Molecular Sequence Data
- Molecular Mimicry
- Molecular Dynamics Simulation
Citation
APA
Chicago
ICMJE
MLA
NLM
Bobay, B. G., DiGennaro, P., Scholl, E., Imin, N., Djordjevic, M. A., & Mck Bird, D. (2013). Solution NMR studies of the plant peptide hormone CEP inform function. FEBS Lett, 587(24), 3979–3985. https://doi.org/10.1016/j.febslet.2013.10.033
Bobay, Benjamin G., Peter DiGennaro, Elizabeth Scholl, Nijat Imin, Michael A. Djordjevic, and David Mck Bird. “Solution NMR studies of the plant peptide hormone CEP inform function.” FEBS Lett 587, no. 24 (December 11, 2013): 3979–85. https://doi.org/10.1016/j.febslet.2013.10.033.
Bobay BG, DiGennaro P, Scholl E, Imin N, Djordjevic MA, Mck Bird D. Solution NMR studies of the plant peptide hormone CEP inform function. FEBS Lett. 2013 Dec 11;587(24):3979–85.
Bobay, Benjamin G., et al. “Solution NMR studies of the plant peptide hormone CEP inform function.” FEBS Lett, vol. 587, no. 24, Dec. 2013, pp. 3979–85. Pubmed, doi:10.1016/j.febslet.2013.10.033.
Bobay BG, DiGennaro P, Scholl E, Imin N, Djordjevic MA, Mck Bird D. Solution NMR studies of the plant peptide hormone CEP inform function. FEBS Lett. 2013 Dec 11;587(24):3979–3985.
Published In
FEBS Lett
DOI
EISSN
1873-3468
Publication Date
December 11, 2013
Volume
587
Issue
24
Start / End Page
3979 / 3985
Location
England
Related Subject Headings
- Tylenchoidea
- Sequence Homology, Amino Acid
- Root Nodules, Plant
- Plants
- Plant Growth Regulators
- Plant Diseases
- Nuclear Magnetic Resonance, Biomolecular
- Molecular Sequence Data
- Molecular Mimicry
- Molecular Dynamics Simulation