Team Approach: Metal Hypersensitivity in Total Joint Arthroplasty.

Journal Article (Journal Article)

»: As total joint arthroplasty volume continues to grow nationwide, more uncommon complications such as metal implant hypersensitivity are reported with greater frequency in the literature. »: Metal hypersensitivity is a challenging diagnosis given the potentially vague symptomology. It should be considered a diagnosis of exclusion, necessitating careful consideration of other potential etiologies of a failing implant before arriving at the final diagnosis of metal hypersensitivity. »: Patients can experience substantial morbidity from implant rejection and in severe, refractory cases may even require revision arthroplasty and conversion to a hypoallergenic implant. »: Given the complex nature of the condition, successful treatment of metal hypersensitivity to orthopaedic implants is best achieved through the use of a multidisciplinary, team-based approach. Immunologists, radiologists, and infectious disease physicians as well as orthopaedic surgeons and mechanical engineers are all vital in appropriate diagnosis and treatment of the condition.

Full Text

Duke Authors

Cited Authors

  • Anastasio, AT; Johnson, LG; Willhite, JP; Mousallem, T; Hendershot, EF; Parekh, SG

Published Date

  • January 1, 2023

Published In

Volume / Issue

  • 11 / 1

PubMed ID

  • 36722837

Electronic International Standard Serial Number (EISSN)

  • 2329-9185

Digital Object Identifier (DOI)

  • 10.2106/JBJS.RVW.22.00157


  • eng

Conference Location

  • United States