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Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed.

Publication ,  Journal Article
Reeve, E; Bayliss, EA; Shetterly, S; Maiyani, M; Gleason, KS; Norton, JD; Sheehan, OC; Green, AR; Maciejewski, ML; Drace, M; Sawyer, J; Boyd, CM
Published in: Age Ageing
January 8, 2023

BACKGROUND: people living with cognitive impairment commonly take multiple medications including potentially inappropriate medications (PIMs), which puts them at risk of medication related harms. AIMS: to explore willingness to have a medication deprescribed of older people living with cognitive impairment (dementia or mild cognitive impairment) and multiple chronic conditions and assess the relationship between willingness, patient characteristics and belief about medications. METHODS: cross-sectional study using results from the revised Patients' Attitudes Towards Deprescribing questionnaire (rPATDcog) collected as baseline data in the OPTIMIZE study, a pragmatic, cluster-randomised trial educating patients and clinicians about deprescribing. Eligible participants were 65+, diagnosed with dementia or mild cognitive impairment, and prescribed at least five-long-term medications. RESULTS: the questionnaire was mailed to 1,409 intervention patients and 553 (39%) were returned and included in analysis. Participants had a mean age of 80.1 (SD 7.4) and 52.4% were female. About 78.5% (431/549) of participants said that they would be willing to have one of their medications stopped if their doctor said it was possible. Willingness to deprescribe was negatively associated with getting stressed when changes are made and with previously having a bad experience with stopping a medication (P < 0.001 for both). CONCLUSION: most older people living with cognitive impairment are willing to deprescribe. Addressing previous bad experiences with stopping a medication and stress when changes are made to medications may be key points to discuss during deprescribing conversations.

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Published In

Age Ageing

DOI

EISSN

1468-2834

Publication Date

January 8, 2023

Volume

52

Issue

1

Location

England

Related Subject Headings

  • Polypharmacy
  • Male
  • Humans
  • Geriatrics
  • Female
  • Deprescriptions
  • Dementia
  • Cross-Sectional Studies
  • Cognitive Dysfunction
  • Caregivers
 

Citation

APA
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Reeve, E., Bayliss, E. A., Shetterly, S., Maiyani, M., Gleason, K. S., Norton, J. D., … Boyd, C. M. (2023). Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed. Age Ageing, 52(1). https://doi.org/10.1093/ageing/afac335
Reeve, Emily, Elizabeth A. Bayliss, Susan Shetterly, Mahesh Maiyani, Kathy S. Gleason, Jonathan D. Norton, Orla C. Sheehan, et al. “Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed.Age Ageing 52, no. 1 (January 8, 2023). https://doi.org/10.1093/ageing/afac335.
Reeve E, Bayliss EA, Shetterly S, Maiyani M, Gleason KS, Norton JD, et al. Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed. Age Ageing. 2023 Jan 8;52(1).
Reeve, Emily, et al. “Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed.Age Ageing, vol. 52, no. 1, Jan. 2023. Pubmed, doi:10.1093/ageing/afac335.
Reeve E, Bayliss EA, Shetterly S, Maiyani M, Gleason KS, Norton JD, Sheehan OC, Green AR, Maciejewski ML, Drace M, Sawyer J, Boyd CM. Willingness of older people living with dementia and mild cognitive impairment and their caregivers to have medications deprescribed. Age Ageing. 2023 Jan 8;52(1).
Journal cover image

Published In

Age Ageing

DOI

EISSN

1468-2834

Publication Date

January 8, 2023

Volume

52

Issue

1

Location

England

Related Subject Headings

  • Polypharmacy
  • Male
  • Humans
  • Geriatrics
  • Female
  • Deprescriptions
  • Dementia
  • Cross-Sectional Studies
  • Cognitive Dysfunction
  • Caregivers