Galectin 3 complements BNP in risk stratification in acute heart failure.
Publication
, Journal Article
Fermann, GJ; Lindsell, CJ; Storrow, AB; Hart, K; Sperling, M; Roll, S; Weintraub, NL; Miller, KF; Maron, DJ; Naftilan, AJ; McPherson, JA ...
Published in: Biomarkers
December 2012
BACKGROUND: Galectin 3 (G3) is a mediator of fibrosis and remodeling in heart failure. METHODS: Patients diagnosed with and treated for Acute Heart Failure Syndromes were prospectively enrolled in the Decision Making in Acute Decompensated Heart Failure multicenter trial. RESULTS: Patients with a higher G3 had a history of renal disease, a lower heart rate and acute kidney injury. They also tended to have a history of HF and 30-day adverse events compared with B-type natriuretic peptide. CONCLUSION: In Acute Heart Failure Syndromes, G3 levels do not provide prognostic value, but when used complementary to B-type natriuretic peptide, G3 is associated with renal dysfunction and may predict 30-day events.
Duke Scholars
Published In
Biomarkers
DOI
EISSN
1366-5804
Publication Date
December 2012
Volume
17
Issue
8
Start / End Page
706 / 713
Location
England
Related Subject Headings
- Toxicology
- Syndrome
- Risk Factors
- Risk Assessment
- Prospective Studies
- Prognosis
- Outcome Assessment, Health Care
- Natriuretic Peptide, Brain
- Middle Aged
- Male
Citation
APA
Chicago
ICMJE
MLA
NLM
Fermann, G. J., Lindsell, C. J., Storrow, A. B., Hart, K., Sperling, M., Roll, S., … Collins, S. P. (2012). Galectin 3 complements BNP in risk stratification in acute heart failure. Biomarkers, 17(8), 706–713. https://doi.org/10.3109/1354750X.2012.719037
Fermann, Gregory J., Christopher J. Lindsell, Alan B. Storrow, Kimberly Hart, Matthew Sperling, Susan Roll, Neal L. Weintraub, et al. “Galectin 3 complements BNP in risk stratification in acute heart failure.” Biomarkers 17, no. 8 (December 2012): 706–13. https://doi.org/10.3109/1354750X.2012.719037.
Fermann GJ, Lindsell CJ, Storrow AB, Hart K, Sperling M, Roll S, et al. Galectin 3 complements BNP in risk stratification in acute heart failure. Biomarkers. 2012 Dec;17(8):706–13.
Fermann, Gregory J., et al. “Galectin 3 complements BNP in risk stratification in acute heart failure.” Biomarkers, vol. 17, no. 8, Dec. 2012, pp. 706–13. Pubmed, doi:10.3109/1354750X.2012.719037.
Fermann GJ, Lindsell CJ, Storrow AB, Hart K, Sperling M, Roll S, Weintraub NL, Miller KF, Maron DJ, Naftilan AJ, McPherson JA, Sawyer DB, Christenson R, Collins SP. Galectin 3 complements BNP in risk stratification in acute heart failure. Biomarkers. 2012 Dec;17(8):706–713.
Published In
Biomarkers
DOI
EISSN
1366-5804
Publication Date
December 2012
Volume
17
Issue
8
Start / End Page
706 / 713
Location
England
Related Subject Headings
- Toxicology
- Syndrome
- Risk Factors
- Risk Assessment
- Prospective Studies
- Prognosis
- Outcome Assessment, Health Care
- Natriuretic Peptide, Brain
- Middle Aged
- Male