Finger systolic blood pressures: effects of cold provocation on the reference finger.

Finger systolic blood pressure measured after cold provocation and ischemia of a digit is used to assist in the diagnosis of vibration-induced white finger, VWF. A reduction in finger systolic blood pressure after cooling is assumed to indicate vascular dysfunction. The percentage pressure change observed in the tested finger is often corrected for whole body effects (systemic systolic pressure changes) according to the pressure change measured in a reference finger. The commonly used method of correction is based on assumptions as to the causes of any changes occurring in the reference finger. It is assumed that the reference finger is not differentially susceptible to the cold provocation of the test finger, arising from either close proximity to the cold provocation or from a vascular disorder in the reference finger. An experiment has been undertaken to investigate the repeatability, over three days, of measurements of the arm systolic pressures of both arms and the finger systolic pressures in air of four fingers of both hands. The systolic pressures of both arms and of four fingers of one hand were also measured whilst the fifth finger of the same hand was subjected to cold provocation at 10 degrees C. Twelve healthy male subjects were rested in a supine position for 15 minutes in a room at 21-24 degrees C before measurements were taken. Finger systolic blood pressures were recorded using strain gauge plethysmography. The results show that the systolic blood pressure measurements were generally repeatable, but differed with measurement location. Cold provocation of the test finger had little consistent effect on the systolic pressures measured at other locations. The results are interpreted with regard to the correction of finger systolic pressure using a reference measurement.

Duke Scholars

Author Christopher Lindsell Biostatistics & Bioinformatics, Division of Biostatistics