Insidious-onset, non-wheezing carteolol-induced asthma in an atopic patient without asthma history.

Journal Article (Journal Article)

Carteolol, a non-selective beta-antagonist with a potential risk of severe bronchial constriction in patients with asthma, is one of the most commonly prescribed medication for managing ocular pressure in glaucoma. We present a case of a 24-year-old woman with a history of atopy but no known asthma who presented an insidious onset of clinical manifestations compatible with drug-induced asthma after the initiation of carteolol for ocular hypertension control. The patient developed progressive chest tightness and dyspnoea for 2 months before the pulmonary function test revealed a positive bronchoprovocation response. She reported significant improvement of respiratory symptoms within 2 weeks after the discontinuation of carteolol, and a negative provocation response was later confirmed by repeat pulmonary function test. In conclusion, eye drops with non-selective beta-antagonising effect can induce asthmatic symptoms in patients without a previous diagnosis of asthma and should be administered with caution in patients with associated risk factors.

Full Text

Duke Authors

Cited Authors

  • Wu, J-H; Jerng, J-S; Su, C-C

Published Date

  • April 4, 2019

Published In

Volume / Issue

  • 12 / 4

PubMed ID

  • 30948417

Pubmed Central ID

  • PMC6453396

Electronic International Standard Serial Number (EISSN)

  • 1757-790X

Digital Object Identifier (DOI)

  • 10.1136/bcr-2019-229343


  • eng

Conference Location

  • England