Skip to main content
Journal cover image

Synchronous Surgical Management of Erectile Dysfunction and Stress Urinary Incontinence: A Systematic Review and Meta-Analysis of Reoperation Rates.

Publication ,  Journal Article
Pyrgidis, N; Barham, DW; Hammad, M; Sokolakis, I; Hatzichristodoulou, G; Lentz, AC; Simhan, J; Yafi, FA; Gross, MS
Published in: Sex Med Rev
October 1, 2022

INTRODUCTION: The efficacy, safety, and postoperative outcomes of synchronous surgery for concomitant erectile dysfunction (ED) and stress urinary incontinence (SUI) remain unclear. OBJECTIVES: We performed a systematic review and meta-analysis to evaluate the available synchronous surgical approaches for concomitant ED and SUI and to assess the reoperation rates compared to asynchronous surgery and surgery only for ED or SUI. METHODS: We searched PubMed, Cochrane Library, and Embase databases until June 2022 for relevant studies. Based on data availability, we performed a meta-analysis of odds ratios (ORs) comparing reoperation rates after synchronous surgery in patients with concomitant ED and SUI versus asynchronous surgery, as well as surgery solely for ED or SUI (PROSPERO: CRD42022326941). RESULTS: We included 18 studies in the systematic review (16,517 patients) and 5 in the meta-analysis. Comparing synchronous implantation of penile prosthesis and artificial urinary sphincter (AUS) versus asynchronous surgery, no statistically significant differences were observed in the reoperation rates [OR:0.98, 95% confidence interval (CI): 0.52-1.84, I2:0%). Comparing synchronous implantation of both penile prosthesis and AUS versus implantation of only a penile prosthesis or an AUS, combined surgery was associated with higher reoperation rates (OR:2.02, 95%CI: 1.29-3.16, I2:36% and OR:1.7, 95%CI: 1.25-2.32, I2:0%, respectively). Synchronous surgery led to high satisfaction rates and significant improvement in ED and SUI. Evidence for the combination of penile prosthesis with a male sling or the ProACT device is low, but data suggests it may be safe and effective. The synchronous placement of a Mini-Jupette sling and penile prosthesis represents a promising treatment modality for the correction of ED and mild SUI and/or climacturia. CONCLUSIONS: Synchronous penile prosthesis and AUS implantation appears safe and effective in patients with severe ED and SUI. Further high-quality studies are mandatory to strengthen the current scarce evidence for synchronous surgery in patients with ED and SUI.

Duke Scholars

Published In

Sex Med Rev

DOI

EISSN

2050-0521

Publication Date

October 1, 2022

Volume

10

Issue

4

Start / End Page

782 / 790

Location

Netherlands

Related Subject Headings

  • Urinary Incontinence, Stress
  • Reoperation
  • Prostatectomy
  • Penile Implantation
  • Male
  • Humans
  • Erectile Dysfunction
  • 3215 Reproductive medicine
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Pyrgidis, N., Barham, D. W., Hammad, M., Sokolakis, I., Hatzichristodoulou, G., Lentz, A. C., … Gross, M. S. (2022). Synchronous Surgical Management of Erectile Dysfunction and Stress Urinary Incontinence: A Systematic Review and Meta-Analysis of Reoperation Rates. Sex Med Rev, 10(4), 782–790. https://doi.org/10.1016/j.sxmr.2022.08.003
Pyrgidis, Nikolaos, David W. Barham, Muhammed Hammad, Ioannis Sokolakis, Georgios Hatzichristodoulou, Aaron C. Lentz, Jay Simhan, Faysal A. Yafi, and Martin S. Gross. “Synchronous Surgical Management of Erectile Dysfunction and Stress Urinary Incontinence: A Systematic Review and Meta-Analysis of Reoperation Rates.Sex Med Rev 10, no. 4 (October 1, 2022): 782–90. https://doi.org/10.1016/j.sxmr.2022.08.003.
Pyrgidis N, Barham DW, Hammad M, Sokolakis I, Hatzichristodoulou G, Lentz AC, et al. Synchronous Surgical Management of Erectile Dysfunction and Stress Urinary Incontinence: A Systematic Review and Meta-Analysis of Reoperation Rates. Sex Med Rev. 2022 Oct 1;10(4):782–90.
Pyrgidis, Nikolaos, et al. “Synchronous Surgical Management of Erectile Dysfunction and Stress Urinary Incontinence: A Systematic Review and Meta-Analysis of Reoperation Rates.Sex Med Rev, vol. 10, no. 4, Oct. 2022, pp. 782–90. Pubmed, doi:10.1016/j.sxmr.2022.08.003.
Pyrgidis N, Barham DW, Hammad M, Sokolakis I, Hatzichristodoulou G, Lentz AC, Simhan J, Yafi FA, Gross MS. Synchronous Surgical Management of Erectile Dysfunction and Stress Urinary Incontinence: A Systematic Review and Meta-Analysis of Reoperation Rates. Sex Med Rev. 2022 Oct 1;10(4):782–790.
Journal cover image

Published In

Sex Med Rev

DOI

EISSN

2050-0521

Publication Date

October 1, 2022

Volume

10

Issue

4

Start / End Page

782 / 790

Location

Netherlands

Related Subject Headings

  • Urinary Incontinence, Stress
  • Reoperation
  • Prostatectomy
  • Penile Implantation
  • Male
  • Humans
  • Erectile Dysfunction
  • 3215 Reproductive medicine