Skip to main content

Six-month blood pressure and glucose control among HIV-infected adults with elevated blood pressure and hyperglycemia in northern Tanzania: A prospective observational study.

Publication ,  Journal Article
Sakita, FM; Prattipati, S; Chick, J; Samu, LP; Maro, AV; Coaxum, L; Galson, SW; Samuel, D; Limkakeng, AT; O'Leary, PR; Kilonzo, KG; Temu, G ...
Published in: PLoS One
2023

BACKGROUND: People with HIV in sub-Saharan Africa are increasingly developing age-related comorbidities. The purpose of this prospective observational study was to describe 6-month outcomes among Tanzanians with HIV and elevated blood pressure or hyperglycemia under current care pathways. METHODS: Adults presenting for routine HIV care were enrolled and underwent blood pressure and blood glucose measurements. Participants with abnormal blood pressure or glucose were referred for further care, as per current guidelines. Participants' blood pressure and point-of-care glucose were re-evaluated during their 6-month follow-up visit. Elevated blood pressure was defined as systolic ≥140 mmHg or diastolic ≥90 mmHg. Hyperglycemia was defined as fasting glucose ≥126 mg/dl or random glucose ≥200 mg/dl. An electrocardiogram was obtained at enrollment and at follow-up. Interim myocardial infarction and interim myocardial ischemia were defined as new pathologic Q waves and new T-wave inversions, respectively. RESULTS: Of 500 participants, 155 had elevated blood pressure and 17 had hyperglycemia at enrolment. At 6-month follow-up, 7 (4.6%) of 155 participants with elevated blood pressure reported current use of an anti-hypertensive medication, 100 (66.2%) had persistent elevated blood pressure, 12 (7.9%) developed interim myocardial infarction, and 13 (8.6%) developed interim myocardial ischemia. Among 17 participants with hyperglycemia, 9 (56%) had persistent hyperglycemia at 6 months and 2 (12.5%) reported current use of an anti-hyperglycemic medication. CONCLUSIONS: Interventions are needed to improve non-communicable disease care pathways among Tanzanians with HIV.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

PLoS One

DOI

EISSN

1932-6203

Publication Date

2023

Volume

18

Issue

5

Start / End Page

e0285472

Location

United States

Related Subject Headings

  • Tanzania
  • Myocardial Infarction
  • Hypertension
  • Hyperglycemia
  • Humans
  • HIV Infections
  • General Science & Technology
  • Blood Pressure
  • Blood Glucose
  • Adult
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Sakita, F. M., Prattipati, S., Chick, J., Samu, L. P., Maro, A. V., Coaxum, L., … Hertz, J. T. (2023). Six-month blood pressure and glucose control among HIV-infected adults with elevated blood pressure and hyperglycemia in northern Tanzania: A prospective observational study. PLoS One, 18(5), e0285472. https://doi.org/10.1371/journal.pone.0285472
Sakita, Francis M., Sainikitha Prattipati, Jordan Chick, Linda P. Samu, Amedeus V. Maro, Lauren Coaxum, Sophie W. Galson, et al. “Six-month blood pressure and glucose control among HIV-infected adults with elevated blood pressure and hyperglycemia in northern Tanzania: A prospective observational study.PLoS One 18, no. 5 (2023): e0285472. https://doi.org/10.1371/journal.pone.0285472.
Sakita, Francis M., et al. “Six-month blood pressure and glucose control among HIV-infected adults with elevated blood pressure and hyperglycemia in northern Tanzania: A prospective observational study.PLoS One, vol. 18, no. 5, 2023, p. e0285472. Pubmed, doi:10.1371/journal.pone.0285472.
Sakita FM, Prattipati S, Chick J, Samu LP, Maro AV, Coaxum L, Galson SW, Samuel D, Limkakeng AT, O’Leary PR, Kilonzo KG, Thielman NM, Temu G, Hertz JT. Six-month blood pressure and glucose control among HIV-infected adults with elevated blood pressure and hyperglycemia in northern Tanzania: A prospective observational study. PLoS One. 2023;18(5):e0285472.

Published In

PLoS One

DOI

EISSN

1932-6203

Publication Date

2023

Volume

18

Issue

5

Start / End Page

e0285472

Location

United States

Related Subject Headings

  • Tanzania
  • Myocardial Infarction
  • Hypertension
  • Hyperglycemia
  • Humans
  • HIV Infections
  • General Science & Technology
  • Blood Pressure
  • Blood Glucose
  • Adult