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Fluoroquinolones and the Risk of Achilles Tendon Disorders: Update on a Neglected Complication.

Publication ,  Journal Article
Godoy-Santos, AL; Bruschini, H; Cury, J; Srougi, M; de Cesar-Netto, C; Fonseca, LF; Maffulli, N
Published in: Urology
March 2018

OBJECTIVE: To evaluate the current evidence and to identify associated risk factors that increase the incidence of this complication. Fluoroquinolone (FQ) has been considered the first-line therapy for uncomplicated urinary infections. FQ has been associated with Achilles tendon disorders, especially during the first month of treatment. METHODS: Data sources searched included PubMed, MEDLINE, and Scopus from January 1988 to June 2017. RESULTS: A total of 79 articles were used, with ciprofloxacin representing the most common drug. CONCLUSION: We found that male gender, advanced age, normal body mass index, chronic renal failure, and concurrent use of corticosteroids increase the risk of Achilles tendon disorders.

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Published In

Urology

DOI

EISSN

1527-9995

Publication Date

March 2018

Volume

113

Start / End Page

20 / 25

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Urinary Tract Infections
  • Tendinopathy
  • Sex Factors
  • Severity of Illness Index
  • Rupture, Spontaneous
  • Retrospective Studies
  • Middle Aged
  • Male
  • Incidence
 

Citation

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ICMJE
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Godoy-Santos, A. L., Bruschini, H., Cury, J., Srougi, M., de Cesar-Netto, C., Fonseca, L. F., & Maffulli, N. (2018). Fluoroquinolones and the Risk of Achilles Tendon Disorders: Update on a Neglected Complication. Urology, 113, 20–25. https://doi.org/10.1016/j.urology.2017.10.017
Godoy-Santos, Alexandre Leme, Homero Bruschini, Jose Cury, Miguel Srougi, Cesar de Cesar-Netto, Lucas F. Fonseca, and Nicola Maffulli. “Fluoroquinolones and the Risk of Achilles Tendon Disorders: Update on a Neglected Complication.Urology 113 (March 2018): 20–25. https://doi.org/10.1016/j.urology.2017.10.017.
Godoy-Santos AL, Bruschini H, Cury J, Srougi M, de Cesar-Netto C, Fonseca LF, et al. Fluoroquinolones and the Risk of Achilles Tendon Disorders: Update on a Neglected Complication. Urology. 2018 Mar;113:20–5.
Godoy-Santos, Alexandre Leme, et al. “Fluoroquinolones and the Risk of Achilles Tendon Disorders: Update on a Neglected Complication.Urology, vol. 113, Mar. 2018, pp. 20–25. Pubmed, doi:10.1016/j.urology.2017.10.017.
Godoy-Santos AL, Bruschini H, Cury J, Srougi M, de Cesar-Netto C, Fonseca LF, Maffulli N. Fluoroquinolones and the Risk of Achilles Tendon Disorders: Update on a Neglected Complication. Urology. 2018 Mar;113:20–25.
Journal cover image

Published In

Urology

DOI

EISSN

1527-9995

Publication Date

March 2018

Volume

113

Start / End Page

20 / 25

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Urinary Tract Infections
  • Tendinopathy
  • Sex Factors
  • Severity of Illness Index
  • Rupture, Spontaneous
  • Retrospective Studies
  • Middle Aged
  • Male
  • Incidence