Methods for reducing biosensor membrane biofouling


Journal Article

The deleterious effect that biofouling has on sensor stability is a serious impediment to the development of long term implanted biosensors. This paper reviews the surface modification strategies currently employed to minimize membrane biofouling of in vivo sensors. Nine sensor modifications are discussed herein: hydrogels, phospholipid-based biomimicry, flow-based systems, Nafion, surfactants, naturally derived materials, covalent attachments, diamond-like carbons, and topology. Copyright (C) 2000 Elsevier Science B.V.

Full Text

Duke Authors

Cited Authors

  • Wisniewski, N; Reichert, M

Published Date

  • January 1, 2000

Published In

Volume / Issue

  • 18 / 3-4

Start / End Page

  • 197 - 219

International Standard Serial Number (ISSN)

  • 0927-7765

Digital Object Identifier (DOI)

  • 10.1016/S0927-7765(99)00148-4

Citation Source

  • Scopus