Prospects for vaccine protection against HIV-1 infection and AIDS.
Publication
, Journal Article
Letvin, NL; Barouch, DH; Montefiori, DC
Published in: Annu Rev Immunol
2002
The rapid and devastating spread of the AIDS epidemic in the developing world as well as the difficulties associated with delivering antiretroviral drugs in affected countries underscore the urgent need for the development of a safe and effective AIDS vaccine. In this review, we discuss recent advances in our understanding of the cellular and humoral immune responses to human immunodeficiency virus type 1 (HIV-1) infection. We then describe vaccine strategies that have been explored and discuss the evidence suggesting that cellular immune responses elicited by novel vaccine modalities may attenuate clinical disease caused by HIV-1.
Duke Scholars
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Published In
Annu Rev Immunol
DOI
ISSN
0732-0582
Publication Date
2002
Volume
20
Start / End Page
73 / 99
Location
United States
Related Subject Headings
- Simian immunodeficiency virus
- Simian Immunodeficiency Virus
- Simian Acquired Immunodeficiency Syndrome
- Primates
- Immunotherapy
- Immunology
- Immunity, Cellular
- Humans
- HIV-1
- HIV Infections
Citation
APA
Chicago
ICMJE
MLA
NLM
Letvin, N. L., Barouch, D. H., & Montefiori, D. C. (2002). Prospects for vaccine protection against HIV-1 infection and AIDS. Annu Rev Immunol, 20, 73–99. https://doi.org/10.1146/annurev.immunol.20.081501.094854
Letvin, Norman L., Dan H. Barouch, and David C. Montefiori. “Prospects for vaccine protection against HIV-1 infection and AIDS.” Annu Rev Immunol 20 (2002): 73–99. https://doi.org/10.1146/annurev.immunol.20.081501.094854.
Letvin NL, Barouch DH, Montefiori DC. Prospects for vaccine protection against HIV-1 infection and AIDS. Annu Rev Immunol. 2002;20:73–99.
Letvin, Norman L., et al. “Prospects for vaccine protection against HIV-1 infection and AIDS.” Annu Rev Immunol, vol. 20, 2002, pp. 73–99. Pubmed, doi:10.1146/annurev.immunol.20.081501.094854.
Letvin NL, Barouch DH, Montefiori DC. Prospects for vaccine protection against HIV-1 infection and AIDS. Annu Rev Immunol. 2002;20:73–99.
Published In
Annu Rev Immunol
DOI
ISSN
0732-0582
Publication Date
2002
Volume
20
Start / End Page
73 / 99
Location
United States
Related Subject Headings
- Simian immunodeficiency virus
- Simian Immunodeficiency Virus
- Simian Acquired Immunodeficiency Syndrome
- Primates
- Immunotherapy
- Immunology
- Immunity, Cellular
- Humans
- HIV-1
- HIV Infections