Importance of bone marrow cytogenetic evaluation before autologous bone marrow transplantation for Hodgkin's disease.
Publication
, Journal Article
Chao, NJ; Nademanee, AP; Long, GD; Schmidt, GM; Donlon, TA; Parker, P; Slovak, ML; Nagasawa, LS; Blume, KG; Forman, SJ
Published in: J Clin Oncol
September 1991
Alkylating agents used either with or without radiation therapy have been associated with the development of myelodysplastic syndrome (MDS) and acute nonlymphoblastic leukemia (ANLL) after treatment of both malignant and nonmalignant disorders. This report describes seven patients with recurrent Hodgkin's disease (HD) evaluated for bone marrow transplantation (BMT) who developed chromosomal abnormalities, and emphasizes the importance of bone marrow cytogenetic studies before bone marrow harvest. Three patients with histologically normal bone marrow underwent autologous BMT and subsequently developed an MDS or ANLL. Four patients had the clonal abnormality detected before bone marrow harvest and did not proceed to BMT.
Duke Scholars
Published In
J Clin Oncol
DOI
ISSN
0732-183X
Publication Date
September 1991
Volume
9
Issue
9
Start / End Page
1575 / 1579
Location
United States
Related Subject Headings
- Transplantation, Homologous
- Translocation, Genetic
- Oncology & Carcinogenesis
- Middle Aged
- Male
- Humans
- Hodgkin Disease
- Female
- Chromosome Aberrations
- Bone Marrow Transplantation
Citation
APA
Chicago
ICMJE
MLA
NLM
Chao, N. J., Nademanee, A. P., Long, G. D., Schmidt, G. M., Donlon, T. A., Parker, P., … Forman, S. J. (1991). Importance of bone marrow cytogenetic evaluation before autologous bone marrow transplantation for Hodgkin's disease. J Clin Oncol, 9(9), 1575–1579. https://doi.org/10.1200/JCO.1991.9.9.1575
Chao, N. J., A. P. Nademanee, G. D. Long, G. M. Schmidt, T. A. Donlon, P. Parker, M. L. Slovak, L. S. Nagasawa, K. G. Blume, and S. J. Forman. “Importance of bone marrow cytogenetic evaluation before autologous bone marrow transplantation for Hodgkin's disease.” J Clin Oncol 9, no. 9 (September 1991): 1575–79. https://doi.org/10.1200/JCO.1991.9.9.1575.
Chao NJ, Nademanee AP, Long GD, Schmidt GM, Donlon TA, Parker P, et al. Importance of bone marrow cytogenetic evaluation before autologous bone marrow transplantation for Hodgkin's disease. J Clin Oncol. 1991 Sep;9(9):1575–9.
Chao, N. J., et al. “Importance of bone marrow cytogenetic evaluation before autologous bone marrow transplantation for Hodgkin's disease.” J Clin Oncol, vol. 9, no. 9, Sept. 1991, pp. 1575–79. Pubmed, doi:10.1200/JCO.1991.9.9.1575.
Chao NJ, Nademanee AP, Long GD, Schmidt GM, Donlon TA, Parker P, Slovak ML, Nagasawa LS, Blume KG, Forman SJ. Importance of bone marrow cytogenetic evaluation before autologous bone marrow transplantation for Hodgkin's disease. J Clin Oncol. 1991 Sep;9(9):1575–1579.
Published In
J Clin Oncol
DOI
ISSN
0732-183X
Publication Date
September 1991
Volume
9
Issue
9
Start / End Page
1575 / 1579
Location
United States
Related Subject Headings
- Transplantation, Homologous
- Translocation, Genetic
- Oncology & Carcinogenesis
- Middle Aged
- Male
- Humans
- Hodgkin Disease
- Female
- Chromosome Aberrations
- Bone Marrow Transplantation