The COBRA family of putative GPI-anchored proteins in Arabidopsis. A new fellowship in expansion.
Journal Article (Journal Article)
Identification of regulatory molecules that determine the extent and direction of expansion is necessary to understand how cell morphogenesis is controlled in plants. We recently identified COB (COBRA) as a key regulator of the orientation of cell expansion in the root. Analysis of the Arabidopsis genome sequence indicated that COB belongs to a multigene family consisting of 12 members, all predicted to encode glycosylphosphatidylinositol-anchored proteins. All but two of the COBL (COB-like) genes are expressed in most organs examined, suggesting possible redundancy. Sequence comparisons, phylogenetic analyses, and exon-intron positions revealed that the COB family is composed of two main subgroups sharing a common architecture, one subgroup being characterized by an additional N-terminal domain. Identification of expressed sequence tags corresponding to potential orthologs in other plant species suggested that COB-related functions are required in all vascular plants. Together, these results indicate that COB family members are likely to be important new players at the plasma membrane-cell wall interface.
Full Text
Duke Authors
Cited Authors
- Roudier, F; Schindelman, G; DeSalle, R; Benfey, PN
Published Date
- October 2002
Published In
Volume / Issue
- 130 / 2
Start / End Page
- 538 - 548
PubMed ID
- 12376623
Pubmed Central ID
- PMC166585
Electronic International Standard Serial Number (EISSN)
- 1532-2548
International Standard Serial Number (ISSN)
- 0032-0889
Digital Object Identifier (DOI)
- 10.1104/pp.007468
Language
- eng