Clostridium difficile associated with pseudomembranous colitis. Occurrence in a 12-week-old infant without prior antibiotic therapy.


Journal Article

In a previously healthy 12-week-old male infant with a two-week history of poor feeding, colic, and bloody stools, pseudomembranous colitis developed. No prior antibiotics were administered although the child had received dicyclomine hydrochloride. Clostridium difficile and its toxin were detected in the child's stool. Severe disseminated intravascular coagulopathy developed; the patient required total colectomy but eventually recovered. Clostridium difficile colonization has not, to our knowledge, been previously documented in infantile pseudomembranous colitis.

Full Text

Duke Authors

Cited Authors

  • Adler, SP; Chandrika, T; Berman, WF

Published Date

  • September 1, 1981

Published In

Volume / Issue

  • 135 / 9

Start / End Page

  • 820 - 822

PubMed ID

  • 7282658

Pubmed Central ID

  • 7282658

International Standard Serial Number (ISSN)

  • 0002-922X


  • eng

Conference Location

  • United States