Combination therapy for early Alzheimer's disease: what are we waiting for?

Journal Article

The practical pharmacological approaches currently available to palliate the cognitive and functional losses in early Alzheimer's disease (AD) include cholinesterase inhibitors (ChEI), antioxidants (e.g., vitamin E), anti-inflammatory agents, estrogen, seligiline, vasoactive agents, and ginkgo biloba. Reviewing available data on these therapies and using models from medical illnesses such as cancer and hypertension, we highlight the urgent need for evaluating combination therapies in early AD.

Full Text

Duke Authors

Cited Authors

  • Doraiswamy, PM; Steffens, DC

Published Date

  • October 1998

Published In

Volume / Issue

  • 46 / 10

Start / End Page

  • 1322 - 1324

PubMed ID

  • 9777922

Pubmed Central ID

  • 9777922

Electronic International Standard Serial Number (EISSN)

  • 1532-5415

International Standard Serial Number (ISSN)

  • 0002-8614

Digital Object Identifier (DOI)

  • 10.1111/j.1532-5415.1998.tb04556.x


  • eng