Pituitary abnormalities in eating disorders: further evidence from MRI studies.

Journal Article (Journal Article)

1. The frequent occurrence of hypothalamo-pituitary dysfunction in patients with eating disorders as well as prior reports that nutritional and endocrine status influence pituitary morphology, led us to hypothesize that pituitary size and shape may be altered in patients with eating disorders. 2. Magnetic resonance imaging (MRI) does not use ionizing radiation and is currently one of the most feasible modalities available to study the pituitary gland in vivo. Using MRI, we have previously reported in a preliminary study that female patients with eating disorders had significantly smaller pituitary glands than controls. In addition MRI excluded any pituitary mass lesions. 3. In this report, we confirm our previous MRI findings and provide further evidence of pituitary abnormalities in an expanded sample of eating disorder patients. Preliminary data on pituitary volume estimates from MRI scans are provided for a subset of patients and controls.

Full Text

Duke Authors

Cited Authors

  • Doraiswamy, PM; Krishnan, KR; Boyko, OB; Husain, MM; Figiel, GS; Palese, VJ; Escalona, PR; Shah, SA; McDonald, WM; Rockwell, WJ

Published Date

  • 1991

Published In

Volume / Issue

  • 15 / 3

Start / End Page

  • 351 - 356

PubMed ID

  • 1862218

International Standard Serial Number (ISSN)

  • 0278-5846

Digital Object Identifier (DOI)

  • 10.1016/0278-5846(91)90066-a


  • eng

Conference Location

  • England