Current and future treatments for cognitive deficits in dementia.

Journal Article (Journal Article)

In this article, we primarily focus on the treatment approaches currently marketed and in advanced stages of development for Alzheimer's disease (AD). Amyloid plaques and neurofibrillary tangles remain the pathologic hallmarks of AD, and much progress has been made in unraveling the molecular biology of these changes. In addition, there is also intense research into inflammatory and oxidative mechanisms as well as vascular and neurochemical alterations in AD. Therapies targeted at these mechanisms are discussed.

Full Text

Duke Authors

Cited Authors

  • McLendon, BM; Chen, GG; Doraiswamy, PM

Published Date

  • February 2000

Published In

Volume / Issue

  • 2 / 1

Start / End Page

  • 20 - 23

PubMed ID

  • 11122927

International Standard Serial Number (ISSN)

  • 1523-3812

Digital Object Identifier (DOI)

  • 10.1007/s11920-000-0037-z


  • eng

Conference Location

  • United States