MR assessment of pituitary gland morphology in healthy volunteers: age- and gender-related differences.

Journal Article (Journal Article)

PURPOSE AND METHODS: High-field MR images at 1.5 T were used to characterize the effects of age and gender on pituitary size and shape in a sample of 71 adult volunteers (40 females), aged 21 to 82 years. FINDINGS: For all subjects, age was inversely correlated with pituitary height (r = -.43, P less than .0002) and cross-sectional area (r = -.35, P less than .0028). Age-specific gender differences were also present in pituitary height and area. A convex upper pituitary margin was more common in females (P = .002) and younger subjects (P = .009). CONCLUSIONS: This study confirms that aging is accompanied by gender-specific changes in pituitary size and shape, and provides normative data that may facilitate evaluation of the pituitary gland in neuroendocrine disorders.

Full Text

Duke Authors

Cited Authors

  • Doraiswamy, PM; Potts, JM; Axelson, DA; Husain, MM; Lurie, SN; Na, C; Escalona, PR; McDonald, WM; Figiel, GS; Ellinwood, EH

Published Date

  • September 1992

Published In

Volume / Issue

  • 13 / 5

Start / End Page

  • 1295 - 1299

PubMed ID

  • 1414818

Pubmed Central ID

  • PMC8335241

International Standard Serial Number (ISSN)

  • 0195-6108


  • eng

Conference Location

  • United States