Interuncal distance as a measure of hippocampal atrophy: normative data on axial MR imaging.


Journal Article

PURPOSE: To assess the effects of age and gender on the interuncal distance measured from MR images. METHODS: High-field strength MR images (axial) of 75 volunteers, 21-82 years old and free of neurologic disorders, were used to measure the interuncal distance. RESULTS: The interuncal distance increased with age (r = 0.66, P < .0001). The mean (SD) interuncal distance for all subjects was 21.4 (4) mm with a range of 12 to 29 mm. CONCLUSIONS: The interuncal distance in healthy subjects is unlikely to exceed 30 mm. Our data may be of clinical significance in view of a previous report stating that the interuncal distance may be enlarged in pathologic hippocampal degeneration, such as in patients with Alzheimer disease.

Full Text

Duke Authors

Cited Authors

  • Doraiswamy, PM; McDonald, WM; Patterson, L; Husain, MM; Figiel, GS; Boyko, OB; Krishnan, KR

Published Date

  • January 1, 1993

Published In

Volume / Issue

  • 14 / 1

Start / End Page

  • 141 - 143

PubMed ID

  • 8427076

Pubmed Central ID

  • 8427076

International Standard Serial Number (ISSN)

  • 0195-6108


  • eng

Conference Location

  • United States