Notch/Delta expression in the developing mouse lung.

Journal Article (Journal Article)

Factors controlling the differentiation of the multipotent embryonic lung endoderm and mesoderm are poorly understood. Recent evidence that Delta-like 1 (Dll1) and other genes in the Notch/Delta signaling pathway are expressed in the embryonic mouse lung suggests that this pathway is important for cell fate decisions and/or the differentiation of lung cell types. Here, we report the localization of transcripts of several genes encoding members of the Notch/Delta pathway in the early mouse lung. Most genes are expressed in specific populations and so may contribute to cell diversification.

Full Text

Duke Authors

Cited Authors

  • Post, LC; Ternet, M; Hogan, BL

Published Date

  • November 2000

Published In

Volume / Issue

  • 98 / 1-2

Start / End Page

  • 95 - 98

PubMed ID

  • 11044610

International Standard Serial Number (ISSN)

  • 0925-4773

Digital Object Identifier (DOI)

  • 10.1016/s0925-4773(00)00432-9


  • eng

Conference Location

  • Ireland