Expression of transforming growth factor beta 2 RNA during murine embryogenesis.

Journal Article (Journal Article)

We have studied the temporal and spatial expression of transforming growth factor beta 2 (TGF beta 2) RNA in mouse embryos from 10.5 days post coitum (p.c.) to 3 days post partum (p.p.) by in situ hybridization analysis. TGF beta 2 RNA is expressed in a variety of tissues including bone, cartilage, tendon, gut, blood vessels, skin and fetal placenta, and is in general found in the mesenchymal component of these tissues. The expression of TGF beta 2 RNA changes during development in a manner consistent with a role for the gene product in mediating mesenchymal-epithelial interactions.

Full Text

Duke Authors

Cited Authors

  • Pelton, RW; Nomura, S; Moses, HL; Hogan, BL

Published Date

  • August 1, 1989

Published In

Volume / Issue

  • 106 / 4

Start / End Page

  • 759 - 767

PubMed ID

  • 2485246

International Standard Serial Number (ISSN)

  • 0950-1991

Digital Object Identifier (DOI)

  • 10.1242/dev.106.4.759


  • eng

Conference Location

  • England