Chromosomal assignments of the genes coding for human types II, III, and IV collagen: a dispersed gene family.

Journal Article

The human type II collagen gene, COL2A1, has been assigned to chromosome 12, the type III gene, COL3A1, to chromosome 2, and one of the type IV genes, COL4A1, to chromosome 13. These assignments were made by using cloned genes as probes on Southern blots of DNA from a panel of mouse/human somatic cell hybrids. The two genes of type I collagen, COL1A1 and COL2A1, have been mapped previously to chromosomes 17 and 7, respectively. This family of conserved genes seems therefore to be dispersed throughout the genome.

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Duke Authors

Hogan, Brigid L. M.

Cited Authors

Solomon, E; Hiorns, LR; Spurr, N; Kurkinen, M; Barlow, D; Hogan, BL; Dalgleish, R

Published Date

May 1, 1985

Published In

Proceedings of the National Academy of Sciences of the United States of America

Volume / Issue

82 / 10

Start / End Page

3330 - 3334

PubMed ID

2987919

International Standard Serial Number (ISSN)

0027-8424

Language

Conference Location

United States