Chromosomal assignments of the genes coding for human types II, III, and IV collagen: a dispersed gene family.
Journal Article (Journal Article)
The human type II collagen gene, COL2A1, has been assigned to chromosome 12, the type III gene, COL3A1, to chromosome 2, and one of the type IV genes, COL4A1, to chromosome 13. These assignments were made by using cloned genes as probes on Southern blots of DNA from a panel of mouse/human somatic cell hybrids. The two genes of type I collagen, COL1A1 and COL2A1, have been mapped previously to chromosomes 17 and 7, respectively. This family of conserved genes seems therefore to be dispersed throughout the genome.
Full Text
Duke Authors
Cited Authors
- Solomon, E; Hiorns, LR; Spurr, N; Kurkinen, M; Barlow, D; Hogan, BL; Dalgleish, R
Published Date
- May 1, 1985
Published In
Volume / Issue
- 82 / 10
Start / End Page
- 3330 - 3334
PubMed ID
- 2987919
Pubmed Central ID
- PMC397769
International Standard Serial Number (ISSN)
- 0027-8424
Digital Object Identifier (DOI)
- 10.1073/pnas.82.10.3330
Language
- eng
Conference Location
- United States