The chromosomal mapping of four genes encoding winged helix proteins expressed early in mouse development.

Published

Journal Article

Members of the winged helix family of transcription factors are required for the normal embryonic development of the mouse. Using the interspecific backcross panel from The Jackson Laboratory, we have determined the chromosomal locations of four genes that encode winged helix containing proteins. Mf1 was assigned to mouse Chromosome 8, Mf2 to Chromosome 4, Mf3 to Chromosome 9, and Mf4 to Chromosome 13. Since Mf3 is located in a region of Chromosome 9 containing many well-characterized mouse mutations such as short ear (se), ashen (ash), and dilute (d), we have analyzed deletion mutants to determine the location of Mf3 more precisely.

Full Text

Duke Authors

Cited Authors

  • Labosky, PA; Winnier, GE; Sasaki, H; Blessing, M; Hogan, BL

Published Date

  • June 1, 1996

Published In

Volume / Issue

  • 34 / 2

Start / End Page

  • 241 - 245

PubMed ID

  • 8661058

Pubmed Central ID

  • 8661058

International Standard Serial Number (ISSN)

  • 0888-7543

Digital Object Identifier (DOI)

  • 10.1006/geno.1996.0275

Language

  • eng

Conference Location

  • United States