Bone morphogenetic proteins in development.
Publication
, Journal Article
Hogan, BL
Published in: Curr Opin Genet Dev
August 1996
The bone morphogenetic proteins (BMPs) constitute a large family of cytokines related to members of the transforming growth factor-beta superfamily. Recent evidence, in particular from gene targeting experiments in the mouse, indicates that BMPs are required for mesoderm formation and for the development and patterning of many different organ systems. Significant progress has also been made in understanding the role of BMPs in gastrulation and neurulation in Xenopus and in identifying genes regulating BMP expression and components of the downstream signaling pathways. Extracellular modifiers of BMP activity may constitute an opposing morphogenetic system.
Duke Scholars
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Published In
Curr Opin Genet Dev
DOI
ISSN
0959-437X
Publication Date
August 1996
Volume
6
Issue
4
Start / End Page
432 / 438
Location
England
Related Subject Headings
- Xenopus Proteins
- Transforming Growth Factor beta
- Pregnancy
- Kidney
- Humans
- Gene Expression Regulation, Developmental
- Female
- Eye
- Extremities
- Embryonic and Fetal Development
Citation
APA
Chicago
ICMJE
MLA
NLM
Hogan, B. L. (1996). Bone morphogenetic proteins in development. Curr Opin Genet Dev, 6(4), 432–438. https://doi.org/10.1016/s0959-437x(96)80064-5
Hogan, B. L. “Bone morphogenetic proteins in development.” Curr Opin Genet Dev 6, no. 4 (August 1996): 432–38. https://doi.org/10.1016/s0959-437x(96)80064-5.
Hogan BL. Bone morphogenetic proteins in development. Curr Opin Genet Dev. 1996 Aug;6(4):432–8.
Hogan, B. L. “Bone morphogenetic proteins in development.” Curr Opin Genet Dev, vol. 6, no. 4, Aug. 1996, pp. 432–38. Pubmed, doi:10.1016/s0959-437x(96)80064-5.
Hogan BL. Bone morphogenetic proteins in development. Curr Opin Genet Dev. 1996 Aug;6(4):432–438.
Published In
Curr Opin Genet Dev
DOI
ISSN
0959-437X
Publication Date
August 1996
Volume
6
Issue
4
Start / End Page
432 / 438
Location
England
Related Subject Headings
- Xenopus Proteins
- Transforming Growth Factor beta
- Pregnancy
- Kidney
- Humans
- Gene Expression Regulation, Developmental
- Female
- Eye
- Extremities
- Embryonic and Fetal Development