Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse.

Journal Article (Journal Article)

We have used cDNA clones for the B1 and B2 subunits of laminin to find restriction fragment length DNA polymorphisms for the genes encoding these polypeptides in the mouse. Three alleles were found for LamB2 and two for LamB1 among the inbred mouse strains. The segregation of these polymorphisms among recombinant inbred strains showed that these genes are tightly linked in the central region of mouse Chromosome 1 between Sas-1 and Ly-m22, 7.4 +/- 3.2 cM distal to the Pep-3 locus. There is no evidence in the mouse for pseudogenes for these proteins.

Full Text

Duke Authors

Cited Authors

  • Elliott, RW; Barlow, D; Hogan, BL

Published Date

  • August 1985

Published In

Volume / Issue

  • 21 / 8

Start / End Page

  • 477 - 484

PubMed ID

  • 2993224

International Standard Serial Number (ISSN)

  • 0883-8364

Digital Object Identifier (DOI)

  • 10.1007/BF02620837


  • eng

Conference Location

  • United States