Identification of a fetal exon in the human fast troponin T gene.
Publication
, Journal Article
Briggs, MM; Maready, M; Schmidt, JM; Schachat, F
Published in: FEBS Lett
August 15, 1994
A developmentally regulated exon has been identified in the 5'-alternatively spliced region of the human fast Troponin T (TnT) gene. Expressed in fetal (but not adult) muscle, this exon is homologous with the fetal exons recently described in the rabbit and rat fast TnT genes. They all exhibit a split codon organization and encode a highly acidic peptide. To determine if the splicing pathways, including the human fetal exon, are also conserved, we defined the major TnT splicing patterns in fetal muscle. They generate fetal TnT 1, fetal TnT 3, and TnT1f, and TnT3f, species previously described in rabbit and rat skeletal muscles.
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Published In
FEBS Lett
DOI
ISSN
0014-5793
Publication Date
August 15, 1994
Volume
350
Issue
1
Start / End Page
37 / 40
Location
England
Related Subject Headings
- Troponin T
- Troponin
- Sequence Alignment
- RNA, Messenger
- Muscles
- Molecular Sequence Data
- Humans
- Gene Amplification
- Fetus
- Exons
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Briggs, M. M., Maready, M., Schmidt, J. M., & Schachat, F. (1994). Identification of a fetal exon in the human fast troponin T gene. FEBS Lett, 350(1), 37–40. https://doi.org/10.1016/0014-5793(94)00729-2
Briggs, M. M., M. Maready, J. M. Schmidt, and F. Schachat. “Identification of a fetal exon in the human fast troponin T gene.” FEBS Lett 350, no. 1 (August 15, 1994): 37–40. https://doi.org/10.1016/0014-5793(94)00729-2.
Briggs MM, Maready M, Schmidt JM, Schachat F. Identification of a fetal exon in the human fast troponin T gene. FEBS Lett. 1994 Aug 15;350(1):37–40.
Briggs, M. M., et al. “Identification of a fetal exon in the human fast troponin T gene.” FEBS Lett, vol. 350, no. 1, Aug. 1994, pp. 37–40. Pubmed, doi:10.1016/0014-5793(94)00729-2.
Briggs MM, Maready M, Schmidt JM, Schachat F. Identification of a fetal exon in the human fast troponin T gene. FEBS Lett. 1994 Aug 15;350(1):37–40.
Published In
FEBS Lett
DOI
ISSN
0014-5793
Publication Date
August 15, 1994
Volume
350
Issue
1
Start / End Page
37 / 40
Location
England
Related Subject Headings
- Troponin T
- Troponin
- Sequence Alignment
- RNA, Messenger
- Muscles
- Molecular Sequence Data
- Humans
- Gene Amplification
- Fetus
- Exons