Ankyrins and cellular targeting of diverse membrane proteins to physiological sites.


Journal Article (Review)

Ankyrins are spectrin-binding proteins that associate via ANK repeats with a variety of ion channels/pumps, calcium release channels and cell adhesion molecules. Recent studies in mice indicate that ankyrins have a physiological role in restricting voltage-gated sodium channels and members of the L1 CAM family of cell adhesion molecules to excitable membranes in the central nervous system and in targeting calcium-release channels to the calcium homeostasis compartment of striated muscle.

Full Text

Duke Authors

Cited Authors

  • Bennett, V; Chen, L

Published Date

  • February 2001

Published In

Volume / Issue

  • 13 / 1

Start / End Page

  • 61 - 67

PubMed ID

  • 11163135

Pubmed Central ID

  • 11163135

Electronic International Standard Serial Number (EISSN)

  • 1879-0410

International Standard Serial Number (ISSN)

  • 0955-0674

Digital Object Identifier (DOI)

  • 10.1016/s0955-0674(00)00175-7


  • eng