Radical pancreatoduodenectomy for cancer of the papilla of Vater.


Journal Article

Over a 22-year span, 87 patients with carcinoma of the papilla of Vater underwent radical pancreatoduodenectomy. No patient was lost to follow-up, and extended observation was possible in most cases: the definitive operation was at least five years earlier than this study in 87% and at least ten years earlier in 73%. Operative mortality was 11.5% among patients who had a single definitive operative procedure and 15.4% among those whose treatment involved reoperation after prior exploration elsewhere. Overall survival rates at two, five, and ten years were 56%, 34%, and 20% respectively. Factors associated with favorable survival were histologic differentiation (Broders grades 1 and 2), absence of nodal metastasis, and papillary histologic characteristics. Noteworthy is the fact that no patient having resection of an undifferentiated carcinoma (Broders grade 3 or 4) survived four years.

Full Text

Cited Authors

  • Akwari, OE; van Heerden, JA; Adson, MA; Baggenstoss, AH

Published Date

  • April 1, 1977

Published In

Volume / Issue

  • 112 / 4

Start / End Page

  • 451 - 456

PubMed ID

  • 192176

Pubmed Central ID

  • 192176

International Standard Serial Number (ISSN)

  • 0004-0010

Digital Object Identifier (DOI)

  • 10.1001/archsurg.1977.01370040103016


  • eng

Conference Location

  • United States