Prevalence of nutrition-related problems among long-term survivors of allogeneic marrow transplantation.

Journal Article

The nutritional status and prevalence of nutrition-related problems in 192 adult and child allogeneic marrow transplant recipients were evaluated 1 year after transplant in a retrospective chart review. Among these patients, 63% exhibited evidence of chronic graft-versus-host disease (GVHD) at the time of nutrition evaluation, including 44% with extensive disease who were receiving immunosuppressive therapy. Oral sensitivity was observed in 23% of all patients reviewed, and frank stomatitis occurred in 8%. The frequency of xerostomia was 18%; anorexia, 8%; reflux symptoms, 7%; diarrhea, 7%; steatorrhea, 5%; dysgeusia, 3%; and limited exercise tolerance because of dyspnea or joint contractures, 4%. Weight loss 3 to 12 months after transplant was experienced by 28%. Nutrition-related problems, changes in anthropometric indexes indicative of suboptimal nutritional status, and inadequate energy intake were observed more frequently in patients with extensive chronic GVHD than in patients without GVHD or in those with limited GVHD. Our findings indicate a high prevalence of nutrition problems among recipients of allogeneic marrow transplantation 1 year after transplant and, further, suggest the need for ongoing, community-based nutrition monitoring after discharge from a transplant center.

Full Text

Duke Authors

Cited Authors

  • Lenssen, P; Sherry, ME; Cheney, CL; Nims, JW; Sullivan, KM; Stern, JM; Moe, G; Aker, SN

Published Date

  • June 1, 1990

Published In

Volume / Issue

  • 90 / 6

Start / End Page

  • 835 - 842

PubMed ID

  • 2345257

International Standard Serial Number (ISSN)

  • 0002-8223

Language

  • eng

Conference Location

  • United States