Hyperimmunoglobulinemia E syndrome: radiographic observations.

Published

Journal Article

Susceptibility to recurrent staphylococcal cutaneous and respiratory infections beginning in infancy associated with extreme hyperimmunoglobulinemia E is a recently described primary immunodeficiency syndrome. Other clinical features include depressed cellular immunity and deficient antibody formation. Recurrent pneumonia and cyst formation with variable persistence and expansion characterized the radiographic couse in 11 patients. Five cysts resolved with continuous antistaphylococcal therapy; 2 were resected without recurrence; and 4 persisted after surgery and/or antibiotics (2--8 years). The cysts had dense, necrotic surfaces with fibrous walls, eosinophilic and other inflammatory cell infiltrates, and frequent, persistent, bronchial connections. Sinusitis (9/9) and mastoiditis (3/4) were also observed radiographically.

Full Text

Duke Authors

Cited Authors

  • Merten, DF; Buckley, RH; Pratt, PC; Effmann, EL; Grossman, H

Published Date

  • July 1, 1979

Published In

Volume / Issue

  • 132 / 1

Start / End Page

  • 71 - 78

PubMed ID

  • 451223

Pubmed Central ID

  • 451223

International Standard Serial Number (ISSN)

  • 0033-8419

Digital Object Identifier (DOI)

  • 10.1148/132.1.71

Language

  • eng

Conference Location

  • United States