Monoclonal immunoglobulin-secreting lymphoma in a patient with severe combined immunodeficiency disease.

Journal Article (Journal Article)

A 3.5 year old boy with X-linked severe combined immunodeficiency disease (SCID), who had been in laminar flow isolation throughout his life, developed a B cell tumour producing up to 3008 mg/dl of an IgM kappa paraprotein 1 month after infusion of both liver and thymus cells from a fetal donor and 6 months after the last of six fetal liver cell infusions given over a 3 year period. Pretransplant studies revealed a high percentage of circulating B lymphocytes. HLA typing suggests that the tumour was of host origin.

Full Text

Duke Authors

Cited Authors

  • Shirley, LR; Buckley, RH; Borowitz, MJ; Welt, SI; Kostyu, DD

Published Date

  • June 1982

Published In

Volume / Issue

  • 48 / 3

Start / End Page

  • 666 - 674

PubMed ID

  • 6811170

Pubmed Central ID

  • PMC1536604

International Standard Serial Number (ISSN)

  • 0009-9104


  • eng

Conference Location

  • England