Regional cerebral blood flow and depersonalization after tetrahydrocannabinol administration.
Published
Journal Article
OBJECTIVE: The aim of this study was to examine the relationship between depersonalization induced by tetrahydrocannabinol (THC), and regional brain activation. METHOD: Cerebral blood flow (CBF) was measured by means of positron emission tomography (PET) in 59 normal right-handed volunteers before and following intravenous infusions of THC. RESULTS: After THC, CBF showed a global increase which was more marked in the right hemisphere, frontal lobes and anterior cingulate. CONCLUSION: Regression analyses showed positive correlations between the right frontal and anterior cingulate and depersonalization.
Full Text
Duke Authors
Cited Authors
- Mathew, RJ; Wilson, WH; Chiu, NY; Turkington, TG; Degrado, TR; Coleman, RE
Published Date
- July 1999
Published In
Volume / Issue
- 100 / 1
Start / End Page
- 67 - 75
PubMed ID
- 10442442
Pubmed Central ID
- 10442442
International Standard Serial Number (ISSN)
- 0001-690X
Digital Object Identifier (DOI)
- 10.1111/j.1600-0447.1999.tb10916.x
Language
- eng
Conference Location
- United States