Skip to main content
Journal cover image

Regional cerebral blood flow and depersonalization after tetrahydrocannabinol administration.

Publication ,  Journal Article
Mathew, RJ; Wilson, WH; Chiu, NY; Turkington, TG; Degrado, TR; Coleman, RE
Published in: Acta Psychiatr Scand
July 1999

OBJECTIVE: The aim of this study was to examine the relationship between depersonalization induced by tetrahydrocannabinol (THC), and regional brain activation. METHOD: Cerebral blood flow (CBF) was measured by means of positron emission tomography (PET) in 59 normal right-handed volunteers before and following intravenous infusions of THC. RESULTS: After THC, CBF showed a global increase which was more marked in the right hemisphere, frontal lobes and anterior cingulate. CONCLUSION: Regression analyses showed positive correlations between the right frontal and anterior cingulate and depersonalization.

Duke Scholars

Published In

Acta Psychiatr Scand

DOI

ISSN

0001-690X

Publication Date

July 1999

Volume

100

Issue

1

Start / End Page

67 / 75

Location

United States

Related Subject Headings

  • Tomography, Emission-Computed
  • Regression Analysis
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Heart Rate
  • Hallucinogens
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Mathew, R. J., Wilson, W. H., Chiu, N. Y., Turkington, T. G., Degrado, T. R., & Coleman, R. E. (1999). Regional cerebral blood flow and depersonalization after tetrahydrocannabinol administration. Acta Psychiatr Scand, 100(1), 67–75. https://doi.org/10.1111/j.1600-0447.1999.tb10916.x
Mathew, R. J., W. H. Wilson, N. Y. Chiu, T. G. Turkington, T. R. Degrado, and R. E. Coleman. “Regional cerebral blood flow and depersonalization after tetrahydrocannabinol administration.Acta Psychiatr Scand 100, no. 1 (July 1999): 67–75. https://doi.org/10.1111/j.1600-0447.1999.tb10916.x.
Mathew RJ, Wilson WH, Chiu NY, Turkington TG, Degrado TR, Coleman RE. Regional cerebral blood flow and depersonalization after tetrahydrocannabinol administration. Acta Psychiatr Scand. 1999 Jul;100(1):67–75.
Mathew, R. J., et al. “Regional cerebral blood flow and depersonalization after tetrahydrocannabinol administration.Acta Psychiatr Scand, vol. 100, no. 1, July 1999, pp. 67–75. Pubmed, doi:10.1111/j.1600-0447.1999.tb10916.x.
Mathew RJ, Wilson WH, Chiu NY, Turkington TG, Degrado TR, Coleman RE. Regional cerebral blood flow and depersonalization after tetrahydrocannabinol administration. Acta Psychiatr Scand. 1999 Jul;100(1):67–75.
Journal cover image

Published In

Acta Psychiatr Scand

DOI

ISSN

0001-690X

Publication Date

July 1999

Volume

100

Issue

1

Start / End Page

67 / 75

Location

United States

Related Subject Headings

  • Tomography, Emission-Computed
  • Regression Analysis
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Heart Rate
  • Hallucinogens
  • Female