Ab interno sclerostomy with a high-powered argon endolaser.

Published

Journal Article

We used a high-energy argon blue-green laser (15-W maximum power output) to create full-thickness sclerostomies from the region of the anterior chamber angle to the subconjunctival space in pigmented rabbits using an ab interno approach. One to four laser pulses delivered through a 300-micron noncontact fiberoptic probe produced patent sclerostomies in all 20 eyes treated using 0.1-second pulse duration and 5 to 14 W of power. No intraoperative complications were encountered. Intraocular pressure, measured in 12 animals, decreased an average of 12 mm Hg in the treated eye relative to the fellow eye on the first postoperative day. The drop in intraocular pressure was associated with formation of a functioning filtration bleb. Intraocular pressure returned to preoperative levels in ten of 12 (83%) of the animals by the fourth postoperative day, and there was an associated flattening of the filtration bleb. Histologic and radioautographic analysis indicated that the effect of the laser was focal. Tissue damage and cellular proliferative response were limited to within approximately 200 micron of the wound margin.

Full Text

Duke Authors

Cited Authors

  • Jaffe, GJ; Williams, GA; Mieler, WF; Radius, RL

Published Date

  • October 15, 1988

Published In

Volume / Issue

  • 106 / 4

Start / End Page

  • 391 - 396

PubMed ID

  • 3177554

Pubmed Central ID

  • 3177554

International Standard Serial Number (ISSN)

  • 0002-9394

Language

  • eng

Conference Location

  • United States