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Histopathologic features of adult-onset foveomacular pigment epithelial dystrophy.

Publication ,  Journal Article
Jaffe, GJ; Schatz, H
Published in: Arch Ophthalmol
July 1988

We studied the clinical and histopathologic characteristics of the eyes obtained after death from a patient with adult-onset foveomacular pigment epithelial dystrophy. The pigmentation seen in the central fovea corresponded histologically to a hyperplastic clump of retinal pigment epithelium. The pale yellow rim surrounding the central pigmentation corresponded histologically to dense periodic acid-Schiff-positive material underlying thinned, atrophic retinal pigment epithelium. Fluorescence microscopy demonstrated homogeneous autofluorescence in the retinal pigment epithelium that was similar in intensity to that of an age-matched control. The results of this clinicopathologic study suggest that in adult-onset foveomacular pigment epithelial dystrophy, an alteration of macular retinal pigment epithelium causes an accumulation of abnormal subretinal pigment epithelial material, photoreceptor degeneration, and serous retinal detachment.

Duke Scholars

Published In

Arch Ophthalmol

DOI

ISSN

0003-9950

Publication Date

July 1988

Volume

106

Issue

7

Start / End Page

958 / 960

Location

United States

Related Subject Headings

  • Visual Acuity
  • Staining and Labeling
  • Retinal Diseases
  • Pigment Epithelium of Eye
  • Ophthalmology & Optometry
  • Microscopy, Fluorescence
  • Male
  • Macula Lutea
  • Humans
  • Fovea Centralis
 

Citation

APA
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ICMJE
MLA
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Jaffe, G. J., & Schatz, H. (1988). Histopathologic features of adult-onset foveomacular pigment epithelial dystrophy. Arch Ophthalmol, 106(7), 958–960. https://doi.org/10.1001/archopht.1988.01060140104034
Jaffe, G. J., and H. Schatz. “Histopathologic features of adult-onset foveomacular pigment epithelial dystrophy.Arch Ophthalmol 106, no. 7 (July 1988): 958–60. https://doi.org/10.1001/archopht.1988.01060140104034.
Jaffe GJ, Schatz H. Histopathologic features of adult-onset foveomacular pigment epithelial dystrophy. Arch Ophthalmol. 1988 Jul;106(7):958–60.
Jaffe, G. J., and H. Schatz. “Histopathologic features of adult-onset foveomacular pigment epithelial dystrophy.Arch Ophthalmol, vol. 106, no. 7, July 1988, pp. 958–60. Pubmed, doi:10.1001/archopht.1988.01060140104034.
Jaffe GJ, Schatz H. Histopathologic features of adult-onset foveomacular pigment epithelial dystrophy. Arch Ophthalmol. 1988 Jul;106(7):958–960.

Published In

Arch Ophthalmol

DOI

ISSN

0003-9950

Publication Date

July 1988

Volume

106

Issue

7

Start / End Page

958 / 960

Location

United States

Related Subject Headings

  • Visual Acuity
  • Staining and Labeling
  • Retinal Diseases
  • Pigment Epithelium of Eye
  • Ophthalmology & Optometry
  • Microscopy, Fluorescence
  • Male
  • Macula Lutea
  • Humans
  • Fovea Centralis