Hydrostatic pulmonary edema. An analysis of lung density changes by computed tomography.

Journal Article (Journal Article)

The computed tomographic (CT) appearance of pulmonary edema induced by elevated left atrial (LA) pressure was examined. Dogs, in the prone position, were scanned during suspended ventilation at functional residual capacity. A surgically implanted LA balloon was inflated to elevate LA pressure for 30 to 140 minutes to a mean pressure of 29.8 mm Hg. Lung water, measured gravimetrically, averaged 14.7 ml/kg body weight compared with 5.7 ml/kg in nonedema control dogs. Lung density in dogs with edema was 69.5% higher than base-line density, while in the control group final lung density was only 4% higher than base line. Analysis of regional density indicated that there were greater increases in density in more central and dependent (ventral) zones of the lung and relatively smaller increases in nondependent (dorsal) peripheral zones. These results are in contrast to the previously reported pattern of density change seen with oleic acid injury in which density increases were primarily in peripheral zones of the lung.

Full Text

Duke Authors

Cited Authors

  • Hedlund, LW; Vock, P; Effmann, EL; Lischko, MM; Putman, CE

Published Date

  • July 1984

Published In

Volume / Issue

  • 19 / 4

Start / End Page

  • 254 - 262

PubMed ID

  • 6480302

International Standard Serial Number (ISSN)

  • 0020-9996

Digital Object Identifier (DOI)

  • 10.1097/00004424-198407000-00004


  • eng

Conference Location

  • United States