Endogenous opiate peptides, stress reactivity, and risk for hypertension.
Publication
, Journal Article
McCubbin, JA; Surwit, RS; Williams, RB
Published in: Hypertension
1985
Endogenous opiate peptides can regulate neuroendocrine and circulatory responses to behavioral stress and may be important in the pathogenic effects of sympathoadrenal reactivity. We tested this hypothesis by examining the effect of the opiate antagonist naloxone on blood pressure responses to behavioral stress in young adults with high, medium, or low casual blood pressures. Naloxone increased mean arterial pressure responses to stress in subjects with low casual pressure, but had no significant effect on responses in subjects with high casual pressure. These results suggest opioidergic inhibition of sympathetic nervous system responses may be deficient in persons at risk for essential hypertension.
Duke Scholars
Published In
Hypertension
DOI
ISSN
0194-911X
Publication Date
1985
Volume
7
Issue
5
Start / End Page
808 / 811
Location
United States
Related Subject Headings
- Stress, Psychological
- Risk
- Naloxone
- Male
- Hypertension
- Humans
- Endorphins
- Cardiovascular System & Hematology
- Blood Pressure
- Adult
Citation
APA
Chicago
ICMJE
MLA
NLM
McCubbin, J. A., Surwit, R. S., & Williams, R. B. (1985). Endogenous opiate peptides, stress reactivity, and risk for hypertension. Hypertension, 7(5), 808–811. https://doi.org/10.1161/01.hyp.7.5.808
McCubbin, J. A., R. S. Surwit, and R. B. Williams. “Endogenous opiate peptides, stress reactivity, and risk for hypertension.” Hypertension 7, no. 5 (1985): 808–11. https://doi.org/10.1161/01.hyp.7.5.808.
McCubbin JA, Surwit RS, Williams RB. Endogenous opiate peptides, stress reactivity, and risk for hypertension. Hypertension. 1985;7(5):808–11.
McCubbin, J. A., et al. “Endogenous opiate peptides, stress reactivity, and risk for hypertension.” Hypertension, vol. 7, no. 5, 1985, pp. 808–11. Pubmed, doi:10.1161/01.hyp.7.5.808.
McCubbin JA, Surwit RS, Williams RB. Endogenous opiate peptides, stress reactivity, and risk for hypertension. Hypertension. 1985;7(5):808–811.
Published In
Hypertension
DOI
ISSN
0194-911X
Publication Date
1985
Volume
7
Issue
5
Start / End Page
808 / 811
Location
United States
Related Subject Headings
- Stress, Psychological
- Risk
- Naloxone
- Male
- Hypertension
- Humans
- Endorphins
- Cardiovascular System & Hematology
- Blood Pressure
- Adult