Characterization of ATP-sensitive potassium channels in intestinal, cholecystokinin-secreting cells.
Publication
, Journal Article
Basavappa, S; Liddle, RA; Mangel, AW
Published in: Biochem Biophys Res Commun
October 28, 1994
In the present study, the electrophysiologic properties of ATP-sensitive potassium channels were evaluated in an intestinal, cholecystokinin-secreting cell line (STC-1). Channels were operative under basal conditions and, in cell-attached membrane patches, channel activity was decreased by glucose or disopyramide, agents which classically inhibit ATP-sensitive potassium channels. Channel activity was increased by the KATP channel opener, diazoxide. Intestinal ATP-sensitive potassium channels appear to behave in a similar manner to those found in cardiac and pancreatic beta cells.
Duke Scholars
Published In
Biochem Biophys Res Commun
DOI
ISSN
0006-291X
Publication Date
October 28, 1994
Volume
204
Issue
2
Start / End Page
855 / 860
Location
United States
Related Subject Headings
- Potassium Channels
- Membrane Potentials
- Intestinal Mucosa
- Disopyramide
- Cholecystokinin
- Cells, Cultured
- Biochemistry & Molecular Biology
- Adenosine Triphosphate
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Basavappa, S., Liddle, R. A., & Mangel, A. W. (1994). Characterization of ATP-sensitive potassium channels in intestinal, cholecystokinin-secreting cells. Biochem Biophys Res Commun, 204(2), 855–860. https://doi.org/10.1006/bbrc.1994.2538
Basavappa, S., R. A. Liddle, and A. W. Mangel. “Characterization of ATP-sensitive potassium channels in intestinal, cholecystokinin-secreting cells.” Biochem Biophys Res Commun 204, no. 2 (October 28, 1994): 855–60. https://doi.org/10.1006/bbrc.1994.2538.
Basavappa S, Liddle RA, Mangel AW. Characterization of ATP-sensitive potassium channels in intestinal, cholecystokinin-secreting cells. Biochem Biophys Res Commun. 1994 Oct 28;204(2):855–60.
Basavappa, S., et al. “Characterization of ATP-sensitive potassium channels in intestinal, cholecystokinin-secreting cells.” Biochem Biophys Res Commun, vol. 204, no. 2, Oct. 1994, pp. 855–60. Pubmed, doi:10.1006/bbrc.1994.2538.
Basavappa S, Liddle RA, Mangel AW. Characterization of ATP-sensitive potassium channels in intestinal, cholecystokinin-secreting cells. Biochem Biophys Res Commun. 1994 Oct 28;204(2):855–860.
Published In
Biochem Biophys Res Commun
DOI
ISSN
0006-291X
Publication Date
October 28, 1994
Volume
204
Issue
2
Start / End Page
855 / 860
Location
United States
Related Subject Headings
- Potassium Channels
- Membrane Potentials
- Intestinal Mucosa
- Disopyramide
- Cholecystokinin
- Cells, Cultured
- Biochemistry & Molecular Biology
- Adenosine Triphosphate
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology