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Expression of T-lymphoblast-encoded HLA-DR, MT, and SB antigens on human T-B lymphoblast hybrids.

Publication ,  Journal Article
Howell, DN; Hartzman, RJ; Cresswell, P
Published in: Hum Immunol
October 1983

The Ia-like antigens of hybrids of the B-lymphoblastoid cell line (B-LCL) WI-L2 and a subline of the T-lymphoblastoid cell line (T-LCL) HSB were examined. Antigens of the HLA-DR and MT series were analyzed by indirect immunofluorescence with chimpanzee anti-DR sera and monoclonal antibodies, and antigens of the SB series were analyzed by primed lymphocyte typing (PLT). The WI-L2 X HSB hybrids expressed antigens of each series not found on either parent cell. In each case, the novel antigens were indistinguishable from those found on SB, a B-LCL established from the same individual as HSB, and are thus presumably HSB encoded.

Duke Scholars

Published In

Hum Immunol

DOI

ISSN

0198-8859

Publication Date

October 1983

Volume

8

Issue

2

Start / End Page

167 / 175

Location

United States

Related Subject Headings

  • T-Lymphocytes
  • Pan troglodytes
  • Lymphocyte Activation
  • Immunology
  • Hybrid Cells
  • Humans
  • Histocompatibility Testing
  • Histocompatibility Antigens Class II
  • HLA-DR Antigens
  • Genetic Code
 

Citation

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MLA
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Howell, D. N., Hartzman, R. J., & Cresswell, P. (1983). Expression of T-lymphoblast-encoded HLA-DR, MT, and SB antigens on human T-B lymphoblast hybrids. Hum Immunol, 8(2), 167–175. https://doi.org/10.1016/0198-8859(83)90011-3
Howell, D. N., R. J. Hartzman, and P. Cresswell. “Expression of T-lymphoblast-encoded HLA-DR, MT, and SB antigens on human T-B lymphoblast hybrids.Hum Immunol 8, no. 2 (October 1983): 167–75. https://doi.org/10.1016/0198-8859(83)90011-3.
Howell DN, Hartzman RJ, Cresswell P. Expression of T-lymphoblast-encoded HLA-DR, MT, and SB antigens on human T-B lymphoblast hybrids. Hum Immunol. 1983 Oct;8(2):167–75.
Howell, D. N., et al. “Expression of T-lymphoblast-encoded HLA-DR, MT, and SB antigens on human T-B lymphoblast hybrids.Hum Immunol, vol. 8, no. 2, Oct. 1983, pp. 167–75. Pubmed, doi:10.1016/0198-8859(83)90011-3.
Howell DN, Hartzman RJ, Cresswell P. Expression of T-lymphoblast-encoded HLA-DR, MT, and SB antigens on human T-B lymphoblast hybrids. Hum Immunol. 1983 Oct;8(2):167–175.
Journal cover image

Published In

Hum Immunol

DOI

ISSN

0198-8859

Publication Date

October 1983

Volume

8

Issue

2

Start / End Page

167 / 175

Location

United States

Related Subject Headings

  • T-Lymphocytes
  • Pan troglodytes
  • Lymphocyte Activation
  • Immunology
  • Hybrid Cells
  • Humans
  • Histocompatibility Testing
  • Histocompatibility Antigens Class II
  • HLA-DR Antigens
  • Genetic Code