Enteric viruses associated with HIV infection in Tanzanian children with chronic diarrhea.

Published

Journal Article

OBJECTIVE: To determine whether specific viruses are associated with HIV infection in Tanzanian children with chronic diarrhea. DESIGN: Cross-sectional survey. SETTING: Major national teaching hospital in Dar es Salaam, Tanzania. PATIENTS: Consecutively admitted, human immunodeficiency virus (HIV)-infected and HIV-uninfected children with chronic diarrhea, and controls without diarrhea, aged 15 months to 5 years. MAIN OUTCOME MEASURE: Enteric viruses identified by electron microscopy (EM) of fecal specimens. RESULTS: Small round structured viruses (SRSV) were more frequent in HIV-infected than HIV-uninfected children with chronic diarrhea (4 of 21 vs 1 of 32, prevalence ratio = 6.09, 90% confidence limits 1.03, 36.14). Rotavirus and coronavirus-like particles (CVLP) were not associated with HIV infection. CONCLUSION: SRSV may be associated with HIV infection in Tanzanian children with chronic diarrhea. Larger, confirmatory studies are needed.

Full Text

Duke Authors

Cited Authors

  • Cegielski, JP; Msengi, AE; Miller, SE

Published Date

  • October 1994

Published In

Volume / Issue

  • 5 / 5

Start / End Page

  • 296 - 299

PubMed ID

  • 11361370

Pubmed Central ID

  • 11361370

International Standard Serial Number (ISSN)

  • 1045-5418

Language

  • eng

Conference Location

  • United States