Enteric viruses associated with HIV infection in Tanzanian children with chronic diarrhea.
Journal Article
OBJECTIVE: To determine whether specific viruses are associated with HIV infection in Tanzanian children with chronic diarrhea. DESIGN: Cross-sectional survey. SETTING: Major national teaching hospital in Dar es Salaam, Tanzania. PATIENTS: Consecutively admitted, human immunodeficiency virus (HIV)-infected and HIV-uninfected children with chronic diarrhea, and controls without diarrhea, aged 15 months to 5 years. MAIN OUTCOME MEASURE: Enteric viruses identified by electron microscopy (EM) of fecal specimens. RESULTS: Small round structured viruses (SRSV) were more frequent in HIV-infected than HIV-uninfected children with chronic diarrhea (4 of 21 vs 1 of 32, prevalence ratio = 6.09, 90% confidence limits 1.03, 36.14). Rotavirus and coronavirus-like particles (CVLP) were not associated with HIV infection. CONCLUSION: SRSV may be associated with HIV infection in Tanzanian children with chronic diarrhea. Larger, confirmatory studies are needed.
Full Text
Duke Authors
Cited Authors
- Cegielski, JP; Msengi, AE; Miller, SE
Published Date
- October 1994
Published In
Volume / Issue
- 5 / 5
Start / End Page
- 296 - 299
PubMed ID
- 11361370
Pubmed Central ID
- 11361370
International Standard Serial Number (ISSN)
- 1045-5418
Language
- eng
Conference Location
- United States