Caveolae as portals of entry for microbes.


Journal Article (Review)

Many pathogens, including many traditionally extracellular microbes, now appear capable of entry into host cells with limited loss of viability. A portal of entry shared by some bacteria, bacterial toxins, viruses and parasites are caveolae (or lipid rafts), which are involved in the import and intracellular translocation of macromolecules in host cells. A requirement for caveolae-mediated endocytosis of microbes appears to be that the respective receptor is a constituent of caveolae or must move to caveolae following ligation.

Full Text

Duke Authors

Cited Authors

  • Shin, JS; Abraham, SN

Published Date

  • July 2001

Published In

Volume / Issue

  • 3 / 9

Start / End Page

  • 755 - 761

PubMed ID

  • 11489424

Pubmed Central ID

  • 11489424

International Standard Serial Number (ISSN)

  • 1286-4579

Digital Object Identifier (DOI)

  • 10.1016/s1286-4579(01)01423-x


  • eng

Conference Location

  • France