A nucleotide change in the anticodon of an Escherichia coli serine transfer RNA results in supD-amber suppression.


Journal Article

The tRNAs specified by the wild type and amber suppressor alleles of the Escherichia coli supD gene have been identified, and their primary structures determined. The sequences differ by a single nucleotide in the middle of the anticodon. A CUA anticodon allows the suppressor tRNA to read the UAG stop codon; the CGA anticodon in the minor serine tRNA species from which the suppressor is derived is specific for the serine codon UCG.

Full Text

Cited Authors

  • Steege, DA

Published Date

  • June 11, 1983

Published In

Volume / Issue

  • 11 / 11

Start / End Page

  • 3823 - 3832

PubMed ID

  • 6344015

Pubmed Central ID

  • 6344015

International Standard Serial Number (ISSN)

  • 0305-1048

Digital Object Identifier (DOI)

  • 10.1093/nar/11.11.3823


  • eng

Conference Location

  • England