Evaluation of the adverse effects of long-term hyposensitization.
Published
Journal Article
This study was undertaken to determine if long-term hyposensitization causes late sequelae, particularly those reflecting aberrant immunologic responses. Atopic individuals receiving five or more years of hyposensitization with allergenic extracts showed no increased autoimmune, collagen vascular, or lymphoproliferative disease. In addition, chronic hyposensitization did not have adverse effects on immunologic reactivity as assessed by a number of immune parameters. Particularly noteworthy was the absence of immune complexes in the serum of patients undergoing long-term hyposensitization. This study represents the first systematic investigation of potential adverse effects of long-term hyposensitization.
Full Text
Cited Authors
- Levinson, AI; Summers, RJ; Lawley, TJ; Evans, R; Frank, MM
Published Date
- August 1, 1978
Published In
Volume / Issue
- 62 / 2
Start / End Page
- 109 - 114
PubMed ID
- 149803
Pubmed Central ID
- 149803
International Standard Serial Number (ISSN)
- 0091-6749
Digital Object Identifier (DOI)
- 10.1016/0091-6749(78)90087-8
Language
- eng
Conference Location
- United States