The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.


Journal Article

The nucleotide sequence of the 948,061 base pairs of chromosome XVI has been determined, completing the sequence of the yeast genome. Chromosome XVI was the last yeast chromosome identified, and some of the genes mapped early to it, such as GAL4, PEP4 and RAD1 (ref. 2) have played important roles in the development of yeast biology. The architecture of this final chromosome seems to be typical of the large yeast chromosomes, and shows large duplications with other yeast chromosomes. Chromosome XVI contains 487 potential protein-encoding genes, 17 tRNA genes and two small nuclear RNA genes; 27% of the genes have significant similarities to human gene products, and 48% are new and of unknown biological function. Systematic efforts to explore gene function have begun.

Full Text

Duke Authors

Cited Authors

  • Bussey, H; Storms, RK; Ahmed, A; Albermann, K; Allen, E; Ansorge, W; Araujo, R; Aparicio, A; Barrell, B; Badcock, K; Benes, V; Botstein, D; Bowman, S; Brückner, M; Carpenter, J; Cherry, JM; Chung, E; Churcher, C; Coster, F; Davis, K; Davis, RW; Dietrich, FS; Delius, H; DiPaolo, T; Hani, J

Published Date

  • May 29, 1997

Published In

Volume / Issue

  • 387 / 6632 Suppl

Start / End Page

  • 103 - 105

PubMed ID

  • 9169875

Pubmed Central ID

  • 9169875

International Standard Serial Number (ISSN)

  • 0028-0836


  • eng

Conference Location

  • England