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The interaction of arsenite with the molybdenum center of chicken liver xanthine dehydrogenase.

Publication ,  Journal Article
Johnson, JL; Rajagopalan, KV
Published in: Bioinorg Chem
1978

Inactivation of chicken liver xanthine dehydrogenase by arsenite is reflected in the molybdenum electron paramagnetic resonance signal at g = 1.97. The arsenite spectrum shows additional splittings and considerable broadening yet remains comparable to the native in total intensity. Further subtle alterations of the molybdenum signal of arsenite-treated enzyme are seen in the presence of purine-type substrates or inhibitors.

Duke Scholars

Published In

Bioinorg Chem

DOI

ISSN

0006-3061

Publication Date

1978

Volume

8

Issue

5

Start / End Page

439 / 444

Location

United States

Related Subject Headings

  • Xanthine Dehydrogenase
  • Protein Binding
  • Molybdenum
  • Liver
  • Ketone Oxidoreductases
  • Electron Spin Resonance Spectroscopy
  • Chickens
  • Arsenic
  • Animals
 

Citation

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Johnson, J. L., & Rajagopalan, K. V. (1978). The interaction of arsenite with the molybdenum center of chicken liver xanthine dehydrogenase. Bioinorg Chem, 8(5), 439–444. https://doi.org/10.1016/s0006-3061(00)80278-1
Johnson, J. L., and K. V. Rajagopalan. “The interaction of arsenite with the molybdenum center of chicken liver xanthine dehydrogenase.Bioinorg Chem 8, no. 5 (1978): 439–44. https://doi.org/10.1016/s0006-3061(00)80278-1.
Johnson, J. L., and K. V. Rajagopalan. “The interaction of arsenite with the molybdenum center of chicken liver xanthine dehydrogenase.Bioinorg Chem, vol. 8, no. 5, 1978, pp. 439–44. Pubmed, doi:10.1016/s0006-3061(00)80278-1.
Johnson JL, Rajagopalan KV. The interaction of arsenite with the molybdenum center of chicken liver xanthine dehydrogenase. Bioinorg Chem. 1978;8(5):439–444.
Journal cover image

Published In

Bioinorg Chem

DOI

ISSN

0006-3061

Publication Date

1978

Volume

8

Issue

5

Start / End Page

439 / 444

Location

United States

Related Subject Headings

  • Xanthine Dehydrogenase
  • Protein Binding
  • Molybdenum
  • Liver
  • Ketone Oxidoreductases
  • Electron Spin Resonance Spectroscopy
  • Chickens
  • Arsenic
  • Animals