Sarcoidosis and its ophthalmic manifestations.

Journal Article (Journal Article)

Of 532 cases of sarcoidosis in the southeastern United States, ocular manifestations were a prominent feature of the disease in 202 (38%) of the patients. Approximately one fifth of them sought medical attention because of ocular complaints. This was the second most frequent clinical manifestation, exceeded only by pulmonary symptoms. When ocular segment structures were affected, the anterior segment was involved in 171 (84.7%) of cases. Chronic granulomatous uveitis was the most common abnormality in 106 cases (52.5%). Posterior segment disease occurred in 51 (25.3%) of cases, usually in the form of chorioretinitis or preiphlebitis; it was sometimes the sole manifestation of ocular sarcoidosis, but usually accompanied abnormalities in the anterior part of the eye. The incidence of central nervous system sarcoidosis was increased when posterior segment involvement was observed. Orbital and adnexal structures, primarily lacrimal gland, were affected in 53 (27.7%) of cases.

Full Text

Duke Authors

Cited Authors

  • Obenauf, CD; Shaw, HE; Sydnor, CF; Klintworth, GK

Published Date

  • November 1, 1978

Published In

Volume / Issue

  • 86 / 5

Start / End Page

  • 648 - 655

PubMed ID

  • 568886

International Standard Serial Number (ISSN)

  • 0002-9394

Digital Object Identifier (DOI)

  • 10.1016/0002-9394(78)90184-8


  • eng

Conference Location

  • United States